Recombinant mouse Cathepsin S protein

Recombinant Protein

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Ctss, as known as cathepsin S isoform 2, is a lysosomal cysteine protease of the papain family. This protein plays a major role in the processing of the MHC class II-associated invariant chain. It has been implicated in the pathogenensis of several diseases such as Alzheimer s disease and degenerative disorders associated with the cells of the mononuclear phagocytic system. Also, it is less abundant in tissues than Cathepsins B, L and H. The highest levels of this protein have been found in lymph nodes, spleen and phagocytic cells. Recombinant mouse Ctss, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Immunology

< 1 EU per 1ug of protein (determined by LAL method)

Mouse