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Recombinant human CRLF2 protein

ArtNr NKM-ATGP3478-10ug
Hersteller NKMAX
Menge 10 ug
Quantity options 10 ug 250 ug 50 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host Baculovirus-Infected Insect Cells
Konjugat/Tag HIS
Purity > 95% by SDS-PAGE
Sequence <ADP>QGGAAEG VQIQIIYFNL ETVQVTWNAS KYSRTNLTFH YRFNGDEAYD QCTNYLLQEG HTSGCLLDAE QRDDILYFSI RNGTHPVFTA SRWMVYYLKP SSPKHVRFSW HQDAVTVTCS DLSYGDLLYE VQYRSPFDTE WQSKQENTCN VTIEGLDAEK CYSFWVRVKA MEDVYGPDTY PSDWSEVTCW QRGEIRDACA ETPTPPKPKL SK<HHHHHH>
Citations Reche PA., et al. (2001) J Immunol. 167:336-343.
Chen IM., et al. (2012) Blood. 119:3512-3522.
NCBI NP_071431.2
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Cytokine receptor-like factor 2 isoform 1 precursor,CRL2,CRLF2Y,TSLPR,Cytokine receptor-like factor 2 isoform 1,CRLF2,Cytokine receptor-like 2,ILXR,Thymic stromal lymphopoietin protein receptor,TSLP receptor
Similar products CRLF2, CRL2, CRLF2Y, TSLPR, TSLP R, Cytokine receptor-like factor 2 isoform 1 precursor, ATGP3478-10ug, ATGP3478-20ug, ATGP3478-50ug, ATGP3478-100ug, ATGP3478-250ug, ATGP3478-500ug, ATGP3478-1mg, ATGP3478-010, ATGP3478-020, ATGP3478-050, ATGP3478-100, ATGP3478-250, ATGP3478-500, ATGP3478-01M
Lieferbar
Manufacturer - Type
Recombinant Protein
Manufacturer - Host
Baculovirus
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
25.2 kDa (218aa)
Description
CRLF2, also known as cytokine receptor-like factor 2 isoform 1, is a receptor for thymic stromal lymphopoietin. It is proposed to signal through a heterodimeric receptor complex that consists of a new member of the hemopoietin family termed CRLF2 and the IL-7R alpha-chain. The protein induces phosphorylation of Stat3 and Stat5 also activate JAK2 pathways. CRLF2 and IL-7R alpha are principally coexpressed on monocytes and dendritic cell populations and to a much lesser extent of various lymphoid cells. Recombinant human CRLF2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Concentration
1mg/ml (determined by absorbance at 280nm)
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Antigen Species
Human
Gene Category
Immunology
Domain
23-231aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Predicted nterm
Ala
Species of Protein
Human
Manufacturer - Search Terms
TSLPR, TSLP R, Cytokine receptor-like factor 2 isoform 1 precursor, CRLF2Y, CRLF2, CRL2, ATGP3478-10ug, ATGP3478-20ug, ATGP3478-50ug, ATGP3478-100ug, ATGP3478-250ug, ATGP3478-500ug, ATGP3478-1mg, ATGP3478-010, ATGP3478-020, ATGP3478-050, ATGP3478-100, ATGP3478-250, ATGP3478-500, ATGP3478-01M

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 10 ug
Lieferbar: In stock
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