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Recombinant human LIF protein

ArtNr NKM-ATGP3533-500ug
Hersteller NKMAX
Menge 500 ug
Quantity options 100 ug 10 ug 20 ug 250 ug 500 ug 50 ug
Kategorie
Typ Proteins
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host Baculovirus-Infected Insect Cells
Konjugat/Tag HIS
Purity > 90% by SDS-PAGE
Sequence <ADP>SPLPITP VNATCAIRHP CHNNLMNQIR SQLAQLNGSA NALFILYYTA QGEPFPNNLD KLCGPNVTDF PPFHANGTEK AKLVELYRIV VYLGTSLGNI TRDQKILNPS ALSLHSKLNA TADILRGLLS NVLCRLCSKY HVGHVDVTYG PDTSGKDVFQ KKKLGCQLLG KYKQIIAVLA QAF<HHHHHH>
Citations Kuphal S., et al, (2013) Exp. Mol. Pathol. 95:156-165.
Liu SC., et al, (2013) J. Clin. Invest. 123:5269-5283.
NCBI NP_002300
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Leukemia inhibitory factor isoform1,LIF,CDF,DIA,HILDA,MLPLI
Similar products LIF, CDF, DIA, HILDA, MLPLI, Leukemia inhibitory factor isoform1, ATGP3533-10ug, ATGP3533-20ug, ATGP3533-50ug, ATGP3533-100ug, ATGP3533-250ug, ATGP3533-500ug, ATGP3533-1mg, ATGP3533-10, ATGP3533-20, ATGP3533-50, ATGP3533-100, ATGP3533-250, ATGP3533-500, ATGP3533-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Manufacturer - Applications
SDS-PAGE, Bioactivity
Manufacturer - Host
Baculovirus
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
20.8 kDa (189aa)
Description
LIF, as known as leukemia inhibitory factor, is a pleiotropic glycoprotein belonging to the LI6 family of cytokines. This protein is involved in growth promotion and cell differentiation of different types of target cells, influence on bone metabolism, embryogenesis and inflammation. It is produced by the adrenal cortex and likely enhances its production of cortisol and aldosterone. Also, it can function as an autocrine growth factor in some pancreatic cancers, but induced differentiation in the leukemic cell line M1. Recombinant human LIF, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Concentration
0.25mg/ml (determined by absorbance at 280nm)
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Antigen Species
Human
Gene Category
Immunology
Domain
23-202aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment Only
Measured in a cell proliferation assay using TF-1 human erythroleukemic cell. The ED50 range ≤ 0.5 ng/ml.
Predicted nterm
Ala
Species of Protein
Human
Manufacturer - Search Terms
LIF, Leukemia inhibitory factor isoform1, LIF, CDF, DIA, HILDA, MLPLI, ATGP3533-10ug, ATGP3533-20ug, ATGP3533-50ug, ATGP3533-100ug, ATGP3533-250ug, ATGP3533-500ug, ATGP3533-1mg, ATGP3533-10, ATGP3533-20, ATGP3533-50, ATGP3533-100, ATGP3533-250, ATGP3533-500, ATGP3533-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 500 ug
Lieferbar: In stock
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