Recombinant human B7-1/CD80 protein

SDS-PAGE, Bioactivity

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

CD80, also known as T-lymphocyte activation antigen CD80, is a member of cell surface immunoglobulin superfamily. This protein can bind to either human or mouse CD28 and CTLA-4. It is expressed on activated B cells, activated T cells, and macrophages. The B7/CD28/CTLA4 pathway has the ability to both positively and negatively regulate immune responses. Therefore, it is considered a promising therapeutic target for autoimmune diseases and various carcinomas. Recombinant human CD80, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Immunology

< 1 EU per 1ug of protein (determined by LAL method)

Val35

B71, CD80, T-lymphocyte activation antigen CD80, CD80, B7, B7-1, B7.1, BB1, CD28LG, CD28LG1, LAB7, ATGP3663-10ug, ATGP3663-20ug, ATGP3663-50ug, ATGP3663-100ug, ATGP3663-250ug, ATGP3663-500ug, ATGP3663-1mg, ATGP3663-10, ATGP3663-20, ATGP3663-50, ATGP3663-100, ATGP3663-250, ATGP3663-500, ATGP3663-1