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Recombinant human CD200R1 protein

ArtNr NKM-ATGP3809-250ug
Hersteller NKMAX
Menge 250 ug
Quantity options 100 ug 10 ug 20 ug 250 ug 500 ug 50 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host Baculovirus-Infected Insect Cells
Konjugat/Tag HIS
Purity > 90% by SDS-PAGE
Sequence <ADL>SSSLCMD EKQITQNYSK VLAEVNTSWP VKMATNAVLC CPPIALRNLI IITWEIILRG QPSCTKAYKK ETNETKETNC TDERITWVSR PDQNSDLQIR TVAITHDGYY RCIMVTPDGN FHRGYHLQVL VTPEVTLFQN RNRTAVCKAV AGKPAAHISW IPEGDCATKQ EYWSNGTVTV KSTCHWEVHN VSTVTCHVSH LTGNKSLYIE LLPVPGAKKS AKL<LEPKSCD
Citations Wright GJ., et al, (2003) J. Immunol. 171:3034-3046.
Liu JQ., et al, (2016) J. Immunol. 197:1489-1497.
NCBI NP_740750
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Cell surface glycoprotein CD200 receptor 1 isoform d,CD200 cell surface glycoprotein receptor,Cell surface glycoprotein OX2 receptor 1,CD200R,CRTR2,MOX2 receptor,MOX2R,OX2R,HCRTR2
Similar products HCRTR2, CD200R1, CD200R, MOX2R, OX2R, Cell surface glycoprotein CD200 receptor 1 isoform d, ATGP3809-10ug, ATGP3809-20ug, ATGP3809-50ug, ATGP3809-100ug, ATGP3809-250ug, ATGP3809-500ug, ATGP3809-1mg, ATGP3809-10, ATGP3809-20, ATGP3809-50, ATGP3809-100, ATGP3809-250, ATGP3809-500, ATGP3809-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Manufacturer - Applications
SDS-PAGE, Bioactivity
Manufacturer - Conjugate / Tag
hIgG-His-Tag
Manufacturer - Host
Baculovirus
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
51.9 kDa (462aa)
Description
CD200R1, also known as cell surface glycoprotein CD200 receptor 1 isoform d, is a transmembrane protein in the immunoglobulin superfamily. This glycoprotein contains on C2 type Ig-like domain and V type Ig-like domain within its extracellular domain and a PTB-signaling motif in cytoplasmic domain. Also, it is expressed on myeloid cells and CD4+ T cells. For function, this receptor is restricted to the surfaces of myeloid lineage cells and the receptor-substrate interaction may function as a myeloid down regulatory signal. Activation of CD200R1 regulates the expression of inflammatory molecules such as tumor necrosis factor (TNF-alpha), interferon and inducible nitric oxide synthase (iNOS). Recombinant human CD200R1, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Concentration
0.25mg/ml (determined by absorbance at 280nm)
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Antigen Species
Human
Gene Category
Immunology
Domain
24-243aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment Only
Measured by its binding ability in a functional ELISA with Human CD200 (CAT# ATGP4013). The ED50 range ≤ 1 ug/ml.
Predicted nterm
Ala
Species of Protein
Human
Manufacturer - Search Terms
CD200R1, Cell surface glycoprotein CD200 receptor 1 isoform d, CD200R1, CD200R, HCRTR2, MOX2R, OX2R, ATGP3809-10ug, ATGP3809-20ug, ATGP3809-50ug, ATGP3809-100ug, ATGP3809-250ug, ATGP3809-500ug, ATGP3809-1mg, ATGP3809-10, ATGP3809-20, ATGP3809-50, ATGP3809-100, ATGP3809-250, ATGP3809-500, ATGP3809-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 250 ug
Lieferbar: In stock
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