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Recombinant human Vitronectin protein

ArtNr NKM-ATGP3849-500ug
Hersteller NKMAX
Menge 500 ug
Quantity options 100 ug 500 ug 50 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host Baculovirus-Infected Insect Cells
Konjugat/Tag HIS
Purity > 90% by SDS-PAGE
Sequence <ADP>DQESCKG RCTEGFNVDK KCQCDELCSY YQSCCTDYTA ECKPQVTRGD VFTMPEDEYT VYDDGEEKNN ATVHEQVGGP SLTSDLQAQS KGNPEQTPVL KPEEEAPAPE VGASKPEGID SRPETLHPGR PQPPAEEELC SGKPFDAFTD LKNGSLFAFR GQYCYELDEK AVRPGYPKLI RDVWGIEGPI DAAFTRINCQ GKTYLFKGSQ YWRFEDGVLD PDYPRNISDG
Citations Yang XP., et al, (2016) Cancer Biomark. 17:271-279.
Min SK., et al, (2017) Cell Death Differ. 25:268-281.
NCBI NP_000629.3
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias VTN,VN,S-protein,Serum-spreading factor,V75,Vitronectin V65 subunit,Vitronectin V10 subunit,Somatomedin-B,Somatomedin B,Complement S-protein
Similar products VTN, Vitronectin, V75, VN, VNT, VitronectinVitronectin, ATGP3849-10ug, ATGP3849-20ug, ATGP3849-50ug, ATGP3849-100ug, ATGP3849-250ug, ATGP3849-500ug, ATGP3849-1mg, ATGP3849-10, ATGP3849-20, ATGP3849-50, ATGP3849-100, ATGP3849-250, ATGP3849-500, ATGP3849-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Manufacturer - Applications
SDS-PAGE, Bioactivity
Manufacturer - Host
Baculovirus
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
53.3 kDa (468aa)
Description
Vitronectin, also known VTN, is a member of the pexin family. It is a cell adhesion and spreading factor found in serum and tissues. This protein interacts with glycosaminoglycans and proteoglycans and is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. It also contains endogenous cleavage sites such as elastase, thrombin and plasmin. This protein binds multiple ligands, including the soluble vitronectin receptor which affects multi-function. Therefore, it is involved in hemostasis, cell migration, as well as tumor malignancy. Recombinant human Vitronectin protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Concentration
0.25mg/ml (determined by Bradford assay)
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Antigen Species
Human
Gene Category
Cardiovascular
Domain
20-478aa
Endotoxin
< 0.1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment Only
Measured by the ability of the immobilized protein to support the adhesion of B16-F10 mouse melanoma cells. When cells are added to VTN coated plates 5ug/ml. This effect is more to 50%.
Predicted nterm
Ala
Species of Protein
Human
Manufacturer - Search Terms
Vitronectin, VitronectinVitronectin, VTN, V75, VN, VNT, ATGP3849-10ug, ATGP3849-20ug, ATGP3849-50ug, ATGP3849-100ug, ATGP3849-250ug, ATGP3849-500ug, ATGP3849-1mg, ATGP3849-10, ATGP3849-20, ATGP3849-50, ATGP3849-100, ATGP3849-250, ATGP3849-500, ATGP3849-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 500 ug
Lieferbar: In stock
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