Recombinant human Reg4 protein

Recombinant Protein

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Reg4, also known regenerating islet-derived protein 4, a member of the regenerating gene family belonging to the calcium (C-type) dependent lectin superfamily. It is calcium-independent lectin displaying mannose-binding specificity and able to maintain carbohydrate recognition activity in an acidic environment. This protein is involved in inflammatory and metaplastic responses because expression of this protein is increased within or near inflammation, dysplasia and metaplasia of the GI epithelium. And this protein is highly expressed in the gastrointestinal tract and markedly up-regulated in colon adenocarcinoma, pancreatic cancer, gastric adenocarcinoma, and inflammatory bowel disease. Recombinant human Reg4 protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Immunology

< 1 EU per 1ug of protein (determined by LAL method)

Human