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Recombinant mouse IL-1Ra/IL1RN protein

ArtNr NKM-ATGP3884-250ug
Hersteller NKMAX
Menge 250 ug
Quantity options 100 ug 10 ug 20 ug 250 ug 500 ug 50 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Mouse (Murine, Mus musculus)
Host E.coli
Konjugat/Tag HIS
Purity > 95% by SDS-PAGE
Sequence <MGSSHHHHHH SSGLVPRGSH MGSHM>RPSGK RPCKMQAFRI WDTNQKTFYL RNNQLIAGYL QGPNIKLEEK IDMVPIDLHS VFLGIHGGKL CLSCAKSGDD IKLQLEEVNI TDLSKNKEED KRFTFIRSEK GPTTSFESAA CPGWFLCTTL EADRPVSLTN TPEEPLIVTK FYFQEDQ
Citations Steinkasserer A., et al. (1992) Genomics. 13(3):654-7.
Langdahl BL., et al. (2000) J Bone Miner Res. 15(3): 403-14.
Hiramoto K, et al. The role of the active oxygen produced from Gp91phox NADPH oxidase on the newborn weight of mouse pups. (Biology and Medicine. 2015){https://go.gale.com/ps/i.do?id=GALE%7CA440917547&sid=googleScholar&v=2.1&it=r&linkaccess=abs&issn=09748369&p=HRCA&sw=w&userGroupName=anon%7E4b2d7215&aty=open-web-entry}
Hiramoto K, et al. Gp91phox NADPH oxidase modulates litter size by regulating mucin1 in the uterus of mice. (Syst Biol Reprod Med. 2017){https://pubmed.ncbi.nlm.nih.gov/28301257/}
Hiramoto K, et al. The Role of gp91phox and the Effect of Tranexamic Acid Administration on Hair Color in Mice. (Int J Mol Sci. 2019){https://pubmed.ncbi.nlm.nih.gov/31151207/}
NCBI NP_001034790
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Interleukin-1 receptor antagonist protein,IL-1RN,IL-1ra,IRAP,IL1 inhibitor,IL1RA
Similar products ICIL-1RA, IL1F3, ATGP1516, IL1ra, ATGP3884-10ug, ATGP3884-20ug, ATGP3884-50ug, ATGP3884-100ug, ATGP3884-250ug, ATGP3884-500ug, ATGP3884-1mg, ATGP3884-010, ATGP3884-020, ATGP3884-050, ATGP3884-100, ATGP3884-250, ATGP3884-500, ATGP3884-01M
Lieferbar
Manufacturer - Type
Recombinant Protein
Manufacturer - Applications
SDS-PAGE, Bioactivity
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
20 kDa (177aa) confirmed by MALDI-TOF
Description
Interleukin 1 receptor antagonist (IL1RN), also known as IL1-RA, is a member of the interleukin 1 cytokine family. IL1RN may represent a reservoir of IL-1 inhibitors, released upon cell death, whose function is no limit the pro-inflammatory signals but most prominently by mononuclear phagocytes and keratinocytes. IL1RN is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Recombinant mouse IL1RN protein, fused to His-tag at N-terminus was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
1mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol
Antigen Species
Mouse
Gene Category
Hormones & Cytokines
Domain
27-178aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment Only
Measured by its ability to inhibit proliferation using D10.G4.1 mouse helper T cells. The ED50 for this effect is less or equal to 60ng/ml with Mouse IL-1 alpha.
Additional Comment Only
ATGP1516 has been replaced with a catalog number ATGP3884.
Species of Protein
Mouse
Manufacturer - Search Terms
ATGP1516, IL1ra, ICIL-1RA, IL1F3, ATGP3884-10ug, ATGP3884-20ug, ATGP3884-50ug, ATGP3884-100ug, ATGP3884-250ug, ATGP3884-500ug, ATGP3884-1mg, ATGP3884-010, ATGP3884-020, ATGP3884-050, ATGP3884-100, ATGP3884-250, ATGP3884-500, ATGP3884-01M, ATGP1516

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 250 ug
Lieferbar: In stock
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