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Recombinant human IFN-alpha/beta R1/IFNAR1 protein

ArtNr NKM-ATGP3894-20ug
Hersteller NKMAX
Menge 20 ug
Quantity options 100 ug 10 ug 20 ug 250 ug 500 ug 50 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host Baculovirus-Infected Insect Cells
Konjugat/Tag HIS
Purity > 95% by SDS-PAGE
Sequence KNLKSPQKVE VDIIDDNFIL RWNRSDESVG NVTFSFDYQK TGMDNWIKLS GCQNITSTKC NFSSLKLNVY EEIKLRIRAE KENTSSWYEV DSFTPFRKAQ IGPPEVHLEA EDKAIVIHIS PGTKDSVMWA LDGLSFTYSL VIWKNSSGVE ERIENIYSRH KIYKLSPETT YCLKVKAALL TSWKIGVYSP VHCIKTTVEN ELPPPENIEV SVQNQNYVLK WDYTYANMTF QV
Citations Richter MF., et al, (1998) J Biol Chem. 273:24723-24729.
Claudinon J., et al, (2009) J. Biol. Chem. 284:24328-24340.
NCBI NP_000620
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias IFN-alpha/beta R1,IFNAR1,AVP,IFN-alpha-REC,IFNAR,IFNBR,IFRC,Interferon alpha/beta receptor 1,IFN-R-1,IFN-alpha/beta receptor 1,Cytokine receptor class-II member 1,Cytokine receptor family 2 member 1,CRF2-1,Type I interferon receptor 1
Similar products IFN-a, b R1, ATGP3894-10ug, ATGP3894-20ug, ATGP3894-50ug, ATGP3894-100ug, ATGP3894-250ug, ATGP3894-500ug, ATGP3894-1mg, ATGP3894-10, ATGP3894-20, ATGP3894-50, ATGP3894-100, ATGP3894-250, ATGP3894-500, ATGP3894-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Manufacturer - Host
Baculovirus
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
47.9 kDa (415aa)
Description
IFN-alpha/beta R1, also known as interferon alpha/beta receptor 1 (IFNAR1), is a member of the class II cytokine receptor family of proteins that form heterodimeric receptor complexes. These receptors are shared and served multiple functions. IFNAR1 and IFNBR1, in association with IFNAR2 and IFNBR2, is required for propagating anti-microbial signal transduction triggered by the type 1 interferons such as IFN-alpha and IFN-beta. Also, binding and activation of it stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. Recombinant Human IFN-alpha/beta R1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Concentration
0.5mg/ml (determined by absorbance at 280nm)
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 20% glycerol
Antigen Species
Human
Gene Category
Hormones & Cytokines
Domain
28-436aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Predicted nterm
Lys28
Species of Protein
Human
Manufacturer - Search Terms
IFN-a, b R1, ATGP3894-10ug, ATGP3894-20ug, ATGP3894-50ug, ATGP3894-100ug, ATGP3894-250ug, ATGP3894-500ug, ATGP3894-1mg, ATGP3894-10, ATGP3894-20, ATGP3894-50, ATGP3894-100, ATGP3894-250, ATGP3894-500, ATGP3894-1, ATGP3894-10ug, ATGP3894-20ug, ATGP3894-50ug, ATGP3894-100ug, ATGP3894-250ug, ATGP3894-500ug, ATGP3894-1mg, ATGP3894-10, ATGP3894-20, ATGP3894-50, ATGP3894-100, ATGP3894-250, ATGP3894-500, ATGP3894-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 20 ug
Lieferbar: In stock
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