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Recombinant human CTLA4 protein

Recombinant human CTLA4 protein

ArtNr	NKM-ATGP3914-10ug
Hersteller	NKMAX
Menge	10 ug
Quantity options	100 ug 10 ug 20 ug 250 ug 500 ug 50 ug
Kategorie	Oncology By Cell Type Carcinoma Peptides & Proteins Recombinant Proteins SDS-PAGE
Typ	Proteins Recombinant
Format	Liquid
Applikationen	SDS-PAGE
Specific against	Human (Homo sapiens)
Host	Baculovirus-Infected Insect Cells
Konjugat/Tag	HIS
Purity	> 95% by SDS-PAGE
Sequence	<ADL>KAMHVAQ PAVVLASSRG IASFVCEYAS PGKATEVRVT VLRQADSQVT EVCAATYMMG NELTFLDDSI CTGTSSGNQV NLTIQGLRAM DTGLYICKVE LMYPPPYYLG IGNGTQIYVI DPEPCPDSD<L EPKSCDKTHT CPPCPAPELL GGPSVFLFPP KPKDTLMISR TPEVTCVVVD VSHEDPEVKF NWYVDGVEVH NAKTKPREEQ YNSTYRVVSV LTVLHQDWLN
Citations	Harper K., et al. (1991) J. Immunol. 147:1037-1044. Teft WA., et al. (2006) Annu. Rev. Immunol. 24:65-97.
NCBI	NP_005205
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Cytotoxic T-lymphocyte protein 4 isoform CTLA4-TM precursor,Cytotoxic T-lymphocyte-associated antigen 4,CTLA-4,CD152,CELIAC3,Celiac disease 3,Insulin-dependent diabetes mellitus 12,IDDM12,CD,GSE
Lieferbar
Manufacturer - Type	Proteins
Manufacturer - Applications	SDS-PAGE, Bioactivity
Manufacturer - Category	Recombinant Protein
Manufacturer - Conjugate / Tag	hIgG-His-Tag
Manufacturer - Host	Baculovirus
Storage Conditions	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight	40.8 kDa (368aa)
Description	CTLA-4, also known as cytotoxic T-lymphocyte protein 4, is a type I transmembrane T cell inhibitory molecule that is a member of the Ig superfamily. The affinity of CTLA-4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. Recombinant human CTLA-4, fused to hIgG His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Concentration	0.5mg/ml (determined by absorbance at 280nm)
Formulation	Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Antigen Species	Human
Gene Category	Immunology
Domain	36-161aa
Endotoxin	< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment Only	The activity is determined by the IL-2 ELISA in a using Jurkat human acute T cell leukemia cells. The ED50 range ≤150ng/ml with Human B7 1/CD80.
Additional Comment Only	ATGP3364 has been replaced with a catalog number ATGP3914.
Predicted nterm	Ala
Species of Protein	Human
Manufacturer - Search Terms	Cytotoxic T lymphocyte protein 4 isoform CTLA4-TM precursor, Cytotoxic T-lymphocyte-associated antigen 4, CTLA 4, CTLA4, CTLA-4, CD 152, CD152, CELIAC3, CELIAC 3, Celiac disease 3, Insulin-dependent diabetes mellitus 12, Insulin dependent diabetes mellitus 12, IDDM 12, IDDM12, CD, GSE, ATGP3914-10ug, ATGP3914-20ug, ATGP3914-50ug, ATGP3914-100ug, ATGP3914-250ug, ATGP3914-500ug, ATGP3914-1mg, ATGP3914-010, ATGP3914-020, ATGP3914-050, ATGP3914-100, ATGP3914-250, ATGP3914-500, ATGP3914-01M, ATGP3364
Manufacturer - Similar Names	Cytotoxic T lymphocyte protein 4 isoform CTLA4-TM precursor, Cytotoxic T-lymphocyte-associated antigen 4, CTLA 4, CTLA4, CTLA-4, CD 152, CD152, CELIAC3, CELIAC 3, Celiac disease 3, Insulin-dependent diabetes mellitus 12, Insulin dependent diabetes mellitus 12, IDDM 12, IDDM12, CD, GSE, ATGP3914-10ug, ATGP3914-20ug, ATGP3914-50ug, ATGP3914-100ug, ATGP3914-250ug, ATGP3914-500ug, ATGP3914-1mg, ATGP3914-010, ATGP3914-020, ATGP3914-050, ATGP3914-100, ATGP3914-250, ATGP3914-500, ATGP3914-01M, ATGP3364

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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NKM-ATGP3914-10ug-datasheet.pdf

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Menge: 10 ug

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Lieferung vsl. bis 04.12.2025

Express-Lieferung: 3 Tage sparen

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