Recombinant human IL-10 protein

SDS-PAGE, Bioactivity

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

IL-10, also known as Interleukin-10, is an anti-inflammatory cytokine. It inhibits the synthesis of pro-inflammatory cytokines like IFN-gamma, IL2, IL3, TNF and GM-CSF produced by activated macrophages and by helper T-cells. This protein has effects in immunoregulation and inflammation and down-regulates the expression of Th1 cytokines, MHC class II antigens, and costimulatory molecules on macrophages. It acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. This protein controls the inflammatory response of macrophages by reprogramming essential metabolic pathways including mTOR signaling. Recombinant human IL-10, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Hormones & Cytokines

< 1 EU per 1ug of protein (determined by LAL method)

Ser19

Interleukin10, Interleukin 10, Interleukin-10, IL-10, IL10, IL 10, Cytokine synthesis inhibitory factor, CSIF, GVHDS, IL10A, TGIF, T-cell growth inhibitory factor, ATGP3920-10ug, ATGP3920-20ug, ATGP3920-50ug, ATGP3920-100ug, ATGP3920-250ug, ATGP3920-500ug, ATGP3920-1mg, ATGP3920-010, ATGP3920-020, ATGP3920-050, ATGP3920-100, ATGP3920-250, ATGP3920-500, ATGP3920-01M