Recombinant human GDNF protein

SDS-PAGE, Bioactivity

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

GDNF, also known as Glial cell-derived neurotrophic factor, is a member of the GDNF family of ligands (GFL). This Protein has been found that GFLs play a role in a number of biological processes including cell survival, neurite outgrowth, cell differentiation and cell migration. It promotes the survival of many types of neurons and signals through GFRa receptors, particularly GFRa1. These neuronal populations die in the course of Parkinson's disease and amyotrophic lateral sclerosis (ALS). GDNF also regulates kidney development and spermatogenesis, and has a powerful and rapid negative (ameliorating) effect on alcohol consumption. Recombinant human GDNF, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol.

Immunology

< 1 EU per 1ug of protein (determined by LAL method)

Ala

, ATGP3942-10ug, ATGP3942-20ug, ATGP3942-50ug, ATGP3942-100ug, ATGP3942-250ug, ATGP3942-500ug, ATGP3942-1mg, ATGP3942-10, ATGP3942-20, ATGP3942-50, ATGP3942-100, ATGP3942-250, ATGP3942-500, ATGP3942-1