Vergleich

Recombinant SARS-CoV Spike RBD protein

ArtNr NKM-ATGP3966-100ug
Hersteller NKMAX
Menge 100 ug
Quantity options 100 ug 10 ug 20 ug 250 ug 500 ug 50 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Coronavirus
Host HEK293
Konjugat/Tag HIS
Purity > 95% by SDS - PAGE
Sequence <DGSM>RVVPSG DVVRFPNITN LCPFGEVFNA TKFPSVYAWE RKKISNCVAD YSVLYNSTFF STFKCYGVSA TKLNDLCFSN VYADSFVVKG DDVRQIAPGQ TGVIADYNYK LPDDFMGCVL AWNTRNIDAT STGNYNYKYR YLRHGKLRPF ERDISNVPFS PDGKPCTPPA LNCYWPLNDY GFYTTTGIGY QPYRVVVLSF ELLNAPATVC GPKL<HHHHHH>
Citations Kukla M., et al, (2020) J Clin Med. 9:1420.
Ayouba A., et al,(2020) J Clin Virol. 129:104521.
Tortorici, M.A. and D. Veesler (2019). Adv. Virus Res. 105:93-116.
Li F, et al, (2005) Science. 309:1864-1868.
Struck AW, et al, (2012) Antiviral Res. 94:288-296.
NCBI NP_828851.1
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias E2 glycoprotein precursor,Spike glycoprotein,S glycoprotein,E2,Peplomer protein,Severe acute repiratory Syndrome-related Coronavirus,SARS,SRAS-CoV,SARS-CoV1
Similar products sars, covid, covid-19, covid19, sars2, Sars-CoV-2 S1, corona, ATGP3966-10ug, ATGP3966-20ug, ATGP3966-50ug, ATGP3966-100ug, ATGP3966-250ug, ATGP3966-500ug, ATGP3966-1mg, ATGP3966-10, ATGP3966-20, ATGP3966-50, ATGP3966-100, ATGP3966-250, ATGP3966-500, ATGP3966-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Manufacturer - Applications
SDS-PAGE, Bioactivity
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
24.8kDa (220aa)
Description
Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV), Middle Eastern Respiratory Syndrome Coronavirus (MERS-CoV), and the recently identified novel Coronavirus (SARS-CoV-2) belong to the Coronaviridae family, genus Betacoronavirus, that has been related to important epidemiological outbreaks. SARS-CoV emerged in 2003 as a significant threat to human health. SARS-CoV has four structural proteins, known as the S (spike), E (envelope), M (membrane), and N (nucleocapsid) proteins. The spike protein, responsible for allowing the virus to attach to and fuse with the membrane of a host cell and is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion. The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. It attaches the virion to the cell membrane by interacting with host receptor, initiating the infection. A metallopeptidase, angiotensin-converting enzyme 2 (ACE-2), has been identified as a functional receptor for SARS-CoV through interaction with a receptor binding domain (RBD) located at the C-terminus of S1 subunit. Recombinant SARS-CoV spike RBD protein fused to His-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques.
Concentration
0.5 mg/ml (determined by Absorbance at 280nm)
Formulation
Liquid. In Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Antigen Species
SARS-CoV
Gene Category
Virus
Domain
306-515aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment Only
Measured by its binding ability in a functional ELISA with Human ACE-2 (CAT# ATGP3963)
Predicted nterm
Asp
Species of Protein
SARS-CoV
Manufacturer - Search Terms
covid-19, covid19, sars, sars2, Sars-CoV-2 S1, covid, corona, ATGP3966-10ug, ATGP3966-20ug, ATGP3966-50ug, ATGP3966-100ug, ATGP3966-250ug, ATGP3966-500ug, ATGP3966-1mg, ATGP3966-10, ATGP3966-20, ATGP3966-50, ATGP3966-100, ATGP3966-250, ATGP3966-500, ATGP3966-1

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
lieferbar

Vergleichen

Auf den Wunschzettel

Angebot anfordern

Lieferzeit anfragen

Technische Frage stellen

Bulk-Anfrage stellen

Fragen zum Produkt?
 
Schließen