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Recombinant canine IL-5 protein

ArtNr NKM-ATGP3985-20ug
Hersteller NKMAX
Menge 20 ug
Quantity options 100 ug 10 ug 20 ug 250 ug 500 ug 50 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Dog (Canine, Canis lupus familiaris)
Host Baculovirus-Infected Insect Cells
Konjugat/Tag HIS
Purity > 90% by SDS - PAGE
Sequence VENPMNRLVA ETLTLLSTHR TWLIGDGNLM IPTPENKNHQ LCIKEVFQGI DTLKNQTAHG EAVDKLFQNL SLIKEHIERQ KKRCAGERWR VTKFLDYLQV FLGVINTEWT PES<HHHHHH>
Citations Martinez-Moczygemba M., et al. (2003) J Allergy Clin Immunol. 112:653-665.
Milburn MV., et al. (1993) Nature. 363:172-176.
NCBI NP_001006951
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Interleukin-5,Eosinophil differentiation factor,T-cell replacing factor,TRF,EDF
Similar products IL-5, IL5, Interleukin-5, Interleukin 5, IL 5, EDF, B-cell growth factor II, BCGF-II, Eosinophil differentiation factor, T-cell replacing factor, TRF, Interleukin5, T cell replacing factor, B cell growth factor II, BCGF I, BCGF II, BCGFI, BCGF-I, BCGFII, ATGP3985-10ug, ATGP3985-20ug, ATGP3985-50ug, ATGP3985-100ug, ATGP3985-250ug, ATGP3985-500ug, ATGP3985-1mg, ATGP3985-010, ATGP3985-020, ATGP3985-050, ATGP3985-100, ATGP3985-250, ATGP3985-500, ATGP3985-01M
Lieferbar
Manufacturer - Type
Recombinant Protein
Manufacturer - Applications
SDS-PAGE, Bioactivity
Manufacturer - Host
Baculovirus
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
13.9kDa (119aa)
Description
IL-5, also known as interleukin-5, is a member of the hematopoietin receptor superfamily and is comprised of a cytokine-specific alpha chain and the common beta chain that is shared among these cytokines for signaling. Through binding to the IL-5 receptor, IL-5 stimulates B cell growth and increases immunoglobulin secretion. It related hematopoietic cytokines that are important for allergic inflammation. It is a lineage-specific cytokine for eosinophilpoiesis and plays an important part in diseases associated with increased eosinophils, such as asthma. Recombinant canine IL-5, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques
Concentration
0.25mg/ml (determined by Absorbance at 280nm)
Formulation
Liquid. In Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Antigen Species
Canine
Gene Category
Immunology, Cancer
Domain
22-134aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment Only
Measured in a cell proliferation assay using TF-1 human erythroleukemic cell. The ED50 range ≤ 15 ng/ml.
Predicted nterm
Val 22
Species of Protein
Canine
Manufacturer - Search Terms
B cell growth factor II, B-cell growth factor II, BCGF I, BCGF II, BCGFI, BCGF-I, BCGFII, BCGF-II, EDF, Eosinophil differentiation factor, IL 5, IL5, IL-5, Interleukin 5, Interleukin5, Interleukin-5, T cell replacing factor, T-cell replacing factor, TRF, ATGP3985-10ug, ATGP3985-20ug, ATGP3985-50ug, ATGP3985-100ug, ATGP3985-250ug, ATGP3985-500ug, ATGP3985-1mg, ATGP3985-010, ATGP3985-020, ATGP3985-050, ATGP3985-100, ATGP3985-250, ATGP3985-500, ATGP3985-01M

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 20 ug
Lieferbar: In stock
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