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Recombinant human FOLR2 protein

ArtNr NKM-ATGP3987-50ug
Hersteller NKMAX
Menge 50 ug
Quantity options 100 ug 10 ug 20 ug 250 ug 500 ug 50 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host HEK293
Konjugat/Tag HIS
Purity > 90% by SDS-PAGE
Sequence QDRTDLLNVC MDAKHHKTKP GPEDKLHDQC SPWKKNACCT ASTSQELHKD TSRLYNFNWD HCGKMEPACK RHFIQDTCLY ECSPNLGPWI QQVNQSWRKE RFLDVPLCKE DCQRWWEDCH TSHTCKSNWH RGWDWTSGVN KCPAGALCRT FESYFPTPAA LCEGLWSHSY KVSNYSRGSG RCIQMWFDSA QGNPNEEVAR FYAAAMHVN<H HHHHH>
Citations Ross, J.F. et al.,1994, Cancer 73:2432.
Joost W van der Heijden J.W. et al., 2009, Arthritis Rheum. 60:12-21.
NCBI NP_000794.3
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Folate receptor beta,FR-beta,Folate receptor 2,Folate receptor,fetal/placental,Placental folate-binding protein,FBP,FBP Protein,BETA-HFR Protein,FBP/PL-1 Protein,FR-BETA Protein,FR-P3 Protein,FRbeta,FR-BETA,FBP/PL-1,BETA-HFR
Similar products ATGP3987-10ug, ATGP3987-20ug, ATGP3987-50ug, ATGP3987-100ug, ATGP3987-250ug, ATGP3987-500ug, ATGP3987-1mg, ATGP3987-10, ATGP3987-20, ATGP3987-50, ATGP3987-100, ATGP3987-250, ATGP3987-500, ATGP3987-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Manufacturer - Applications
SDS-PAGE, Bioactivity
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
25.1 kDa (215aa)
Description
FOLR2, also known as Folate receptor beta, is a member of the folate receptor (FLOR) family. Members of this gene family have a high affinity for folate and folic acid analogs at neutral pH. And they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. It was originally thought to exist only in placenta, but is also expressed in placenta, cells of the neutrophilic lineage, and some CD34+ hematopoietic progenitor cells. FOLR2 is also upregulated on macrophages and monocytes at chronic inflammatory sites including rheumatoid arthritis synovium and glioblastoma. Recombinant human FOLR2, fused to His-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques.
Concentration
0.25mg/ml (determined by absorbance at 280nm)
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Antigen Species
Human
Gene Category
Signal Transduction, Metabolism
Domain
22-230aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment Only
Measured by its binding ability in a functional ELISA with Folic Acid-BSA. The ED50 range ≤ 5 ug/ml.
Predicted nterm
Gln 22
Species of Protein
Human
Manufacturer - Search Terms
, ATGP3987-10ug, ATGP3987-20ug, ATGP3987-50ug, ATGP3987-100ug, ATGP3987-250ug, ATGP3987-500ug, ATGP3987-1mg, ATGP3987-10, ATGP3987-20, ATGP3987-50, ATGP3987-100, ATGP3987-250, ATGP3987-500, ATGP3987-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ug
Lieferbar: In stock
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