Recombinant human LYVE-1 protein

Recombinant Protein

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

LYVE-1 is also known as XLKD1 and may function in lympathic hyaluronan transport and have a role in tumor metastasis. This Protein is a Link domain-containing hyaladherin, a protein capable of binding to hyaluronic acid (HA), homologous to CD44, the main HA receptor. It is primarily expressed on both the luminal and abluminal surfaces of lymphatic vessels but is also observed in normal liver blood sinusoids, and embryonic blood vessels. It is selective marker of the lymphatic endothelium, is a surface endocytic receptor for hyaluronan (HA), which is an extracellular glycosaminoglycan involved in cell adhesion and migration. Recombinant human LYVE-1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Liquid in. 20mM Tris-HCl buffer (pH 7.5) containing 10% glycerol

Cardiovascular

< 1 EU per 1ug of protein (determined by LAL method)

Human

Lymphatic vessel endothelial hyaluronan receptor 1, CRSBP-1, HAR, LYVE-1, XLKD1, LYVE1, Lymphatic vessel endothelial hyaluronan receptor 1 CRSBP 1, CRSBP1, extracellular link domain containing 1, extracellular link domain-containing 1, hyaluronic acid receptor, LYVE 1, Lymphatic endothelium specific hyaluronan receptor