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Recombinant mouse ACE-2 protein

ArtNr NKM-ATGP4014-500ug
Hersteller NKMAX
Menge 500 ug
Quantity options 100 ug 10 ug 20 ug 250 ug 500 ug 50 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Mouse (Murine, Mus musculus)
Host Baculovirus-Infected Insect Cells
Konjugat/Tag HIS
Purity > 95% by SDS-PAGE
Sequence QSLTEENAKT FLNNFNQEAE DLSYQSSLAS WNYNTNITEE NAQKMSEAAA KWSAFYEEQS KTAQSFSLQE IQTPIIKRQL QALQQSGSSA LSADKNKQLN TILNTMSTIY STGKVCNPKN PQECLLLEPG LDEIMATSTD YNSRLWAWEG WRAEVGKQLR PLYEEYVVLK NEMARANNYN DYGDYWRGDY EAEGADGYNY NRNQLIEDVE RTFAEIKPLY EHLHAYVRRK LM
Citations Kuba K., et al. (2005) Nature Med. 11:875-879.
Ima Y., et al. (2005) Nature 436:112-116.
NCBI NP_081562.2
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Angiotensin-converting enzyme 2,ACE-related carboxypeptidase,Processed Angiotensin-converting enzyme 2,ACE2,2010305L05Rik
Similar products ATGP3288, ATGP4014-10ug, ATGP4014-20ug, ATGP4014-50ug, ATGP4014-100ug, ATGP4014-250ug, ATGP4014-500ug, ATGP4014-1mg, ATGP4014-10, ATGP4014-20, ATGP4014-50, ATGP4014-100, ATGP4014-250, ATGP4014-500, ATGP4014-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Manufacturer - Applications
SDS-PAGE, Enzyme Activity
Manufacturer - Host
Baculovirus
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
84.5 kDa (731aa)
Description
ACE-2, also known as angiotensin-converting enzyme 2, is an integral membrane protein and a zinc metalloprotease of the ACE family that also includes somatic and germinal ACE. It cleaves angiotensin 1 to angiotensin 1-9 and angiotensin 2 to angiotensin 1-7 as a carboxypeptidase. It may be an important regulator of heart function and have a protective role in acute lung injury. Also, it is a key SARS-CoV Spike protein receptor in vivo. Recombinant mouse ACE-2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Concentration
1mg/ml (determined by absorbance at 280nm)
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Antigen Species
Mouse
Gene Category
Enzymes & Proteases
Domain
18-740aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment Only
Specific activity is > 200 pmol/min/ug, and is defined as the amount of enzyme that hydrolysis 1.0 pmole of Mca-YVADAPK(Dnp)-OH per minute at pH 7.5, at 25C.
Predicted nterm
Gln18
Species of Protein
Mouse
Manufacturer - Search Terms
ATGP3288, ATGP4014-10ug, ATGP4014-20ug, ATGP4014-50ug, ATGP4014-100ug, ATGP4014-250ug, ATGP4014-500ug, ATGP4014-1mg, ATGP4014-10, ATGP4014-20, ATGP4014-50, ATGP4014-100, ATGP4014-250, ATGP4014-500, ATGP4014-1, ATGP4014-10ug, ATGP4014-20ug, ATGP4014-50ug, ATGP4014-100ug, ATGP4014-250ug, ATGP4014-500ug, ATGP4014-1mg, ATGP4014-10, ATGP4014-20, ATGP4014-50, ATGP4014-100, ATGP4014-250, ATGP4014-500, ATGP4014-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 500 ug
Lieferbar: In stock
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