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Recombinant human DR3/TNFRSF25 protein

ArtNr NKM-ATGP4017-500ug
Hersteller NKMAX
Menge 500 ug
Quantity options 100 ug 10 ug 20 ug 250 ug 500 ug 50 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host Baculovirus-Infected Insect Cells
Konjugat/Tag HIS
Purity > 90% by SDS-PAGE
Sequence <ADP>QGGTRSP RCDCAGDFHK KIGLFCCRGC PAGHYLKAPC TEPCGNSTCL VCPQDTFLAW ENHHNSECAR CQACDEQASQ VALENCSAVA DTRCGCKPGW FVECQVSQCV SSSPFYCQPC LDCGALHRHT RLLCSRRDTD CGTCLPGFYE HGDGCVSCPT STLGSCPERC AAVCGWRQ<LE PKSCDKTHTC PPCPAPELLG GPSVFLFPPK PKDTLMISRT PEVTCVVVDV
Citations Slebioda TJ., et al. (2011) Eur J Immunol. 41:2606-2611.
Fang L., et al. (2008) J Exp Medl. 205:1037-1048.
NCBI NP_003781.1
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Tumor necrosis factor receptor superfamily member 25,Apo-3,Apoptosis-inducing receptor AIR,Apoptosis-mediating receptor DR3,Apoptosis-mediating receptor TRAMP,Death receptor 3,Lymphocyte-associated receptor of death,LARD,Protein WSL,Protein WSL-1,APO3,DDR3,DR3,TNFRSF12,WSL,WSL1,TR3
Similar products ATGP3375, ATGP4017-10ug, ATGP4017-20ug, ATGP4017-50ug, ATGP4017-100ug, ATGP4017-250ug, ATGP4017-500ug, ATGP4017-1mg, ATGP4017-10, ATGP4017-20, ATGP4017-50, ATGP4017-100, ATGP4017-250, ATGP4017-500, ATGP4017-1
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Manufacturer - Type
Recombinant Protein
Manufacturer - Applications
SDS-PAGE, Bioactivity
Manufacturer - Conjugate / Tag
hIgG-His-Tag
Manufacturer - Host
Baculovirus
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
46.1kDa (417aa)
Description
TNFRSF25, also known as Tumor necrosis factor receptor superfamily member 25, is a member of the TNF receptor superfamily that binds to the TNF-like protein TL1A. TNFRSF25 signals are required to exert T helper cell 2 effector function in Th2-polarized CD4 cells and co-stimulate interleukin-13 production by glycosphingolipidactivated NKT cells. Its axis is a novel immune pathway that participates in the pathogenesis of a variety of autoimmune rheumatic diseases. These molecules may be promising therapeutic targets for inflammatory arthritis. Recombinant human TNFRSF25, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Concentration
0.25mg/ml (determined by absorbance at 280nm)
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Antigen Species
Human
Gene Category
Apoptosis
Domain
25-199aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment Only
Measured by its binding ability in a functional ELISA with Human TL1A/TNFSF15 (CAT# ATGP1049). The ED50 range ≤ 5 ug/ml.
Predicted nterm
Ala
Species of Protein
Human
Manufacturer - Search Terms
ATGP3375, ATGP4017-10ug, ATGP4017-20ug, ATGP4017-50ug, ATGP4017-100ug, ATGP4017-250ug, ATGP4017-500ug, ATGP4017-1mg, ATGP4017-10, ATGP4017-20, ATGP4017-50, ATGP4017-100, ATGP4017-250, ATGP4017-500, ATGP4017-1, ATGP4017-10ug, ATGP4017-20ug, ATGP4017-50ug, ATGP4017-100ug, ATGP4017-250ug, ATGP4017-500ug, ATGP4017-1mg, ATGP4017-10, ATGP4017-20, ATGP4017-50, ATGP4017-100, ATGP4017-250, ATGP4017-500, ATGP4017-1
Manufacturer - Alternative Names
Tumor necrosis factor receptor superfamily member 25, Apo-3, Apoptosis-inducing receptor AIR, Apoptosis-mediating receptor DR3, Apoptosis-mediating receptor TRAMP, Death receptor 3, Lymphocyte-associated receptor of death, LARD, Protein WSL, Protein WSL-1, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1, TR3

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 500 ug
Lieferbar: In stock
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