Recombinant human IL-17E/IL-25 protein

Recombinant Protein

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

IL-25, also known as IL-17E, belongs to the IL-17 cytokine family. It support the Th2 immune response, and has been shown to induce the production of IL-4, IL-5 and IL-13. This is in contrast to other IL-17 family members which promote Th1- and Th17-biased inflammation. Because IL-25 promotes the development of a Th2 immune response, it acts to protect against several bowel infections caused by helminths. It is also referred to as the regulator of IL-9 production. IL-25 has been shown to increase the production of IL-9 in Th9 cells. Another function of this protein is the activation of natural lymphoid cells. IL-25 and IL-33 are the most potent activators of ILC2. IL-25 has potent antitumor activity in vivo in several human cancers including melanoma, breast, lung, colon, and pancreatic cancers, suggesting the potential clinical use of IL-17E as an anticancer agent. Recombinant human IL-17E/IL-25, fused to His-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques.

Liquid. In Phosphate-Buffered Saline (pH 7.4) containing 20% glycerol

Immunology, Hormones & Cytokines

< 1 EU per 1ug of protein (determined by LAL method)

Asp

ATGP4018-10ug, ATGP4018-20ug, ATGP4018-50ug, ATGP4018-100ug, ATGP4018-250ug, ATGP4018-500ug, ATGP4018-1mg, ATGP4018-10, ATGP4018-20, ATGP4018-50, ATGP4018-100, ATGP4018-250, ATGP4018-500, ATGP4018-1, ATGP4018-10ug, ATGP4018-20ug, ATGP4018-50ug, ATGP4018-100ug, ATGP4018-250ug, ATGP4018-500ug, ATGP4018-1mg, ATGP4018-10, ATGP4018-20, ATGP4018-50, ATGP4018-100, ATGP4018-250, ATGP4018-500, ATGP4018-1