Recombinant human Complexin-1 protein

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Complexin1 belongs to a family of SNARE complex binding proteins that were suggested to be either facilitators or inhibitors of vesicle exocytosis. Complexin 1 exhibits reduced Ca2+-triggered fast neurotransmitter release at hippocampal glutamatergic synapses, indicating that this protein is a positive regulator of transmitter release. In contrast, it inhibits SNARE-mediated liposome and cell fusions in vitro, which lead to the hypothesis that it acts as fusion clamps of synaptic exocytosis. Recombinant Complexin 1 protein was expressed in E. coli and purified by using conventional chromatography techniques.

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Neuroscience

< 1 EU per 1ug of protein (determined by LAL method)

Complexin1, CPXL1, CPX1, Synaphin-2, Complexin 1, Complexin I, CPX1, Synaphin 2, CPX0901-10ug, CPX0901-20ug, CPX0901-50ug, CPX0901-100ug, CPX0901-250ug, CPX0901-500ug, CPX0901-1mg, CPX0901-10, CPX0901-20, CPX0901-50, CPX0901-100, CPX0901-250, CPX0901-500, CPX0901-1