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Recombinant human CRADD protein

ArtNr NKM-CRA0901-20ug
Hersteller NKMAX
Menge 20 ug
Quantity options 100 ug 20 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 95% by SDS-PAGE
Sequence MGSSHHHHHH SSGLVPRGSH MEARDKQVLR SLRLELGAEV LVEGLVLQYL YQEGILTENH IQEINAQTTG LRKTMLMLDI LPSRGPKAFD TFLDSLQEFP WVREKLKKAR EEAMTDLPAG DRLTGIPSHI LNSSPSDRQI NQLAQRLGPE WEPMVLSLGL SQTDIYRCKA NHPHNVQSQV VEAFIRWRQR FGKQATFQSL HNGLRAVEVD PSLLLHMLE
Citations Park HH., (2006). J Mol Biol. 357(2):358-64.
Chou JJ., (1998) Ceil. 94(2):171-80.
NCBI NP_003796
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Caspase and RIP adapter with death domain,RAIDD,CRADD,Caspase and RIP adapter with death domain,Caspase and RIP adapter with death domain CASP2 and RIPK1 domain containing adaptor with death domain,Death adaptor molecule RAIDD,Death domain containing protein CRADD,MGC9163,RIP associated ICH1/CED3 homologous protein with death domain,RIP associated protein with a death domain.
Similar products RAIDD, CRADD, Caspase and RIP adapter with death domain, MGC9163, Death adaptor molecule RAIDD, Death domain containing protein CRADD, RIP associated ICH1/CED3 homologous protein with death domain, Caspase and RIP adapter with death domain CASP2 and RIPK1 domain containing adaptor with death domain, RIP associated protein with a death domain., CRA0901-10ug, CRA0901-20ug, CRA0901-50ug, CRA0901-100ug, CRA0901-250ug, CRA0901-500ug, CRA0901-1mg, CRA0901-10, CRA0901-20, CRA0901-50, CRA0901-100, CRA0901-250, CRA0901-500, CRA0901-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
24.9 kDa (219aa) confirmed by MALDI-TOF
Description
CRADD is a 22 kDa, widely-expressed cytosolic adaptor protein. CRADD is a death domain (CARD/DD) containing protein and has been shown to induce cell apoptosis. Through its CARD domain, this protein interacts with, and thus recruits, caspase 2/ICH1 to the cell death signal transduction complex that includes tumor necrosis factor receptor 1 (TNFR1A), RIPK1/RIP kinase, and numbers of other CARD domain-containing proteins. Recombinant CRADD protein was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
1mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 20% glycerol 1mM DTT
Antigen Species
Human
Gene Category
Cancer
Domain
1-199aa
Species of Protein
Human
Manufacturer - Search Terms
CRADD, Caspase and RIP adapter with death domain, RAIDD, CRADD, Caspase and RIP adapter with death domain, Caspase and RIP adapter with death domain CASP2 and RIPK1 domain containing adaptor with death domain, Death adaptor molecule RAIDD, Death domain containing protein CRADD, MGC9163, RIP associated ICH1/CED3 homologous protein with death domain, RIP associated protein with a death domain., CRA0901-10ug, CRA0901-20ug, CRA0901-50ug, CRA0901-100ug, CRA0901-250ug, CRA0901-500ug, CRA0901-1mg, CRA0901-10, CRA0901-20, CRA0901-50, CRA0901-100, CRA0901-250, CRA0901-500, CRA0901-1
Manufacturer - Alternative Names
Caspase and RIP adapter with death domain, RAIDD, CRADD, Caspase and RIP adapter with death domain, Caspase and RIP adapter with death domain CASP2 and RIPK1 domain containing adaptor with death domain, Death adaptor molecule RAIDD, Death domain containing protein CRADD, MGC9163, RIP associated ICH1/CED3 homologous protein with death domain, RIP associated protein with a death domain.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 20 ug
Lieferbar: In stock
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