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Recombinant human FIH-1/HIF-1AN protein

ArtNr NKM-HIF0904-20ug
Hersteller NKMAX
Menge 20 ug
Quantity options 100 ug 20 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag Untagged
Purity > 90% by SDS-PAGE
Sequence MAATAAEAVA SGSGEPREEA GALGPAWDES QLRSYSFPTR PIPRLSQSDP RAEELIENEE PVVLTDTNLV YPALKWDLEY LQENIGNGDF SVYSASTHKF LYYDEKKMAN FQNFKPRSNR EEMKFHEFVE KLQDIQQRGG EERLYLQQTL NDTVGRKIVM DFLGFNWNWI NKQQGKRGWG QLTSNLLLIG MEGNVTPAHY DEQQNFFAQI KGYKRCILFP PDQFECLYPY PV
Citations Fukuba H., et al. (2008) Neurosci Lett. 433(3):209-14.
Li J., et al. (2007) Mol Cell Biol. 27(20):7345-53.
NCBI NP_060372
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Hypoxia-inducible factor 1 alpha subunit inhibitor,Hypoxia-inducible factor asparagine hydroxylase,Factor inhibiting HIF-1,FIH1,Hypoxia-inducible factor 1,alpha subunit inhibitor Hypoxia inducible factor asparagine hydroxylase,Factor inhibiting HIF1,FIH 1,FLJ20615,FLJ22027,Hypoxia inducible factor 1 alpha inhibitor,Hypoxia inducible factor 1 alpha subunit inhibitor,Peptide aspartate beta dioxygenase,DKFZp762F1811,Hypoxia-Inducible Factor-1 Alpha Inhibitor
Similar products HIF1AN, FIH1, HIF0904-10ug, HIF0904-20ug, HIF0904-50ug, HIF0904-100ug, HIF0904-250ug, HIF0904-500ug, HIF0904-1mg, HIF0904-10, HIF0904-20, HIF0904-50, HIF0904-100, HIF0904-250, HIF0904-500, HIF0904-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
40.2 kDa (349aa) confirmed by MALDI-TOF
Description
Hypoxia-inducible factor 1, alpha subunit inhibitor (HIF1AN), a member of the Fe2+ and 2-oxoglutarate-dependent dioxygenase superfamily, is protein that hydoxylates a specific asparagine residue (Asn-803) within the HIF1alpha C-terminal transactivation domain. In normoxia, the HIF1AN-mediated hydroxylation of the HIF1alpha transactivation domain results in blockage of the HIF1alpha-p300/CBP interaction and represses transcriptional activity of HIF1alpha-targeted genes. Recombinant human HIF1AN protein was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
1mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0)
Antigen Species
Human
Gene Category
Cell Cycle
Domain
1-349aa
Species of Protein
Human
Manufacturer - Search Terms
FIH1, HIF1AN, HIF0904-10ug, HIF0904-20ug, HIF0904-50ug, HIF0904-100ug, HIF0904-250ug, HIF0904-500ug, HIF0904-1mg, HIF0904-10, HIF0904-20, HIF0904-50, HIF0904-100, HIF0904-250, HIF0904-500, HIF0904-1
Manufacturer - Alternative Names
Hypoxia-inducible factor 1 alpha subunit inhibitor, Hypoxia-inducible factor asparagine hydroxylase, Factor inhibiting HIF-1, FIH1, Hypoxia-inducible factor 1, alpha subunit inhibitor Hypoxia inducible factor asparagine hydroxylase, Factor inhibiting HIF1, FIH 1, FLJ20615, FLJ22027, Hypoxia inducible factor 1 alpha inhibitor, Hypoxia inducible factor 1 alpha subunit inhibitor, Peptide aspartate beta dioxygenase, DKFZp762F1811, Hypoxia-Inducible Factor-1 Alpha Inhibitor

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 20 ug
Lieferbar: In stock
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