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Recombinant human HSP70/HSPA1A protein

ArtNr NKM-HSP0603-20ug
Hersteller NKMAX
Menge 20 ug
Quantity options 100 ug 20 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 95% by SDS-PAGE
Sequence <MGSSHHHHHH SSGLVPRGSH> MAKAAAIGID LGTTYSCVGV FQHGKVEIIA NDQGNRTTPS YVAFTDTERL IGDAAKNQVA LNPQNTVFDA KRLIGRKFGD PVVQSDMKHW PFQVINDGDK PKVQVSYKGD TKAFYPEEIS SMVLTKMKEI AEAYLGYPVT NAVITVPAYF NDSQRQATKD AGVIAGLNVL RIINEPTAAA IAYGLDRTGK GERNVLIFDL GGGTFDVSIL
Citations Gething M-J, et al. (1992). Nature. 355. 33-45
Lewis MJ, et al. EMBO J. (1985) 4:3137-3143
Kawakami F, et al. Stimulatory effect of α-synuclein on the tau-phosphorylation by GSK-3β. (FEBS J. 2011){https://pubmed.ncbi.nlm.nih.gov/21985244/}
Roy A, et al. Mast Cell Chymase Degrades the Alarmins Heat Shock Protein 70, Biglycan, HMGB1, and Interleukin-33 (IL-33) and Limits Danger-induced Inflammation. (J Biol Chem. 2014){https://www.ncbi.nlm.nih.gov/pubmed/24257755}
Kaiser F, et al. Monocyte cytokine synthesis in response to extracellular cell stress proteins suggests these proteins exhibit network behaviour. (Cell Stress Chaperones. 2014){https://pubmed.ncbi.nlm.nih.gov/23775284/}
NCBI NP_005336.3
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Heat shock 70kDa protein 1A,Heat shock protein family A member 1A,HSP70,HSP70.1,HSP70-1/HSP70-2,HSPA1,HSPA1A,HSPA1B
Similar products HSP70, HSPA1A, HSPA1B, HSPA1, HSP70.1, HSP 70, HSP70-1/HSP70-2, Heat shock 70 kDa protein 1A, Heat shock 70kDa protein 1A, Heat shock protein family A member 1A, HSP0603-10ug, HSP0603-20ug, HSP0603-50ug, HSP0603-100ug, HSP0603-250ug, HSP0603-500ug, HSP0603-1mg, HSP0603-010, HSP0603-020, HSP0603-050, HSP0603-100, HSP0603-250, HSP0603-500, HSP0603-01M
Lieferbar
Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
72.2 kDa (661aa) confirmed by MALDI-TOF
Description
Hsp70 is a human heat shock protein. Hsp70 is an important part of the cell's machinery for protein folding, and help to protect cells from stress. In most species, there are many proteins that belong to the hsp70 family. Some of these are only expressed under stress conditions, while some are present in cells under normal growth conditions and are not heat-inducible. They can be found in different cellular compartments (nuclear, cytosolic, mitochondrial, endoplasmic reticulum, etc... ). Recombinant human Hsp70, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
1mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 7.5) containing 2mM DTT
Antigen Species
Human
Gene Category
Heat Shock Proteins
Domain
1-641aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Species of Protein
Human
Manufacturer - Search Terms
Heat shock 70 kDa protein 1A, Heat shock 70kDa protein 1A, Heat shock protein family A member 1A, HSP 70, HSP70, HSP70.1, HSP70-1/HSP70-2, HSPA1, HSPA1A, HSPA1B, HSP0603-10ug, HSP0603-20ug, HSP0603-50ug, HSP0603-100ug, HSP0603-250ug, HSP0603-500ug, HSP0603-1mg, HSP0603-010, HSP0603-020, HSP0603-050, HSP0603-100, HSP0603-250, HSP0603-500, HSP0603-01M

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 20 ug
Lieferbar: In stock
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