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Recombinant human HTRA2/OMI (S306A) protein

ArtNr NKM-HTR0501-20ug
Hersteller NKMAX
Menge 20 ug
Quantity options 100 ug 20 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 95% by SDS-PAGE
Sequence MAVPSPPPAS PRSQYNFIAD VVEKTAPAVV YIEILDRHPF LGREVPISNG SGFVVAADGL IVTNAHVVAD RRRVRVRLLS GDTYEAVVTA VDPVADIATL RIQTKEPLPT LPLGRSADVR QGEFVVAMGS PFALQNTITS GIVSSAQRPA RDLGLPQTNV EYIQTDAAID FGNAGGPLVN LDGEVIGVNT MKVTAGISFA IPSDRLREFL HRGEKKNSSS GISGSQRRYI GV
Citations Savopoulos JW., et al., (2000) Protein Expr. Purif. 19, 227-34
Gray CW, et al., (2000) Eur. J. Biochem. 267, 5699-710
Martins LM, et al., (2002) J. Biol. Chem. 277, 439-44
Van Loo G, et al., (2002) Cell Death Differ. 9, 20-60
NCBI NP_037379.1
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias HtrA serine peptidase 2,High temperature requirement protein A2,HtrA2,Omi stress-regulated endoprotease,Serine protease 25,Serine proteinase OMI,PRSS25,OMI,PARK13
Similar products HtrA2, OMI, HTRA2, mitochondrial, PRSS25, Serine protease HTRA2, High temperature requirement protein A2, Omi stress-regulated endoprotease, Serine protease 25, Serine proteinase OMI, HtrA2/Omi, EC 3.4.21.108, Omi (S306A), HTR0501-10ug, HTR0501-20ug, HTR0501-50ug, HTR0501-100ug, HTR0501-250ug, HTR0501-500ug, HTR0501-1mg, HTR0501-10, HTR0501-20, HTR0501-50, HTR0501-100, HTR0501-250, HTR0501-500, HTR0501-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
36 kDa (334aa) confirmed by MALDI-TOF
Description
HtrA2/Omi is a mammalian serine protease at high temperatures and has a chaperone activity at low temperature. The full-length HtrA2 is synthesized as a precursor protein and then targeted to the mitochondria where it is matured by the removal of N-terminal 133 residues. Mature HtrA2 consists of a putative transmembrane domain; an inhibitor of apoptosis protein (IAP) -binding motif; a single C-terminal PDZ domain that mediates protein-protein interactions. Recently, HtrA2 has known to contribute both to caspase-dependent and caspase-independent cell death. Mature form of HtrA2/Omi (residues 134-458) was overexpressed in E. coli, and purified by conventional column chromatography techniques.
Concentration
0.5mg/ml (determined by Bradford assay)
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 20% glycerol
Antigen Species
Human
Gene Category
Enzymes & Proteases
Domain
134-458aa
Species of Protein
Human
Manufacturer - Search Terms
HtrA2, Omi (S306A), High temperature requirement protein A2, HTRA2, OMI, PRSS25, HtrA2/Omi, EC 3.4.21.108, High temperature requirement protein A2, HtrA2, Omi stress-regulated endoprotease, Serine proteinase OMI, Serine protease 25, Serine protease HTRA2, mitochondrial, High temperature requirement protein A2, HTR0501-10ug, HTR0501-20ug, HTR0501-50ug, HTR0501-100ug, HTR0501-250ug, HTR0501-500ug, HTR0501-1mg, HTR0501-10, HTR0501-20, HTR0501-50, HTR0501-100, HTR0501-250, HTR0501-500, HTR0501-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 20 ug
Lieferbar: In stock
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