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Recombinant human Hexokinase 3 protein

ArtNr NKM-HXK0701-20ug
Hersteller NKMAX
Menge 20 ug
Quantity options 100 ug 20 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 95% by SDS-PAGE
Sequence <MGSSHHHHHH SSGLVPRGSH> MDSIGSSGLR QGEETLSCSE EGLPGPSDSS ELVQECLQQF KVTRAQLQQI QASLLGSMEQ ALRGQASPAP AVRMLPTYVG STPHGTEQGD FVVLELGATG ASLRVLWVTL TGIEGHRVEP RSQEFVIPQE VMLGAGQQLF DFAAHCLSEF LDAQPVNKQG LQLGFSFSFP CHQTGLDRST LISWTKGFRC SGVEGQDVVQ LLRDAIRRQG
Citations Jon E. et al.,(2003) J.Exp Biology. 206 : 2049-2057
Furuta H. et al.,(1996) Genomics. 1996
36(1):206-9.

Tsumura Y, et al. TMG-123, a novel glucokinase activator, exerts durable effects on hyperglycemia without increasing triglyceride in diabetic animal models. (PLoS One. 2017){https://pubmed.ncbi.nlm.nih.gov/28207836/}
NCBI NP_002106.2
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias HK3,Hexokinase 3,EC 2.7.1.1,Hexokinase type III,HK III,Hexokinase-3,HKIII,Hexokinase3,HK3,HXK3.
Similar products HK3, Hexokinase-3, Hexokinase type III, Hexokinase 3, HKIII, Hexokinase3, HK III, EC 2.7.1.1, HXK3., HXK0701-10ug, HXK0701-20ug, HXK0701-50ug, HXK0701-100ug, HXK0701-250ug, HXK0701-500ug, HXK0701-1mg, HXK0701-10, HXK0701-20, HXK0701-50, HXK0701-100, HXK0701-250, HXK0701-500, HXK0701-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
101.1 kDa (943aa)
Description
Hexokinase is the first enzyme in the glycolytic pathway, catalyzing the transfer of a phosphoryl group from ATP to glucose to form glucose-6-phosphate and ADP. In mammals, four distinct enzymes-types 1 to 4 hexokinases-have been identified. The enzyme is found in most cells, but there is tissue specificity for the particular type of hexokinase. Hexokinase3 lacks the hydrophobic N-terminal sequence critical for targeting to mitochondria. Hexpkinase3 may have anabolic functions, providing H6P for glycogen or lipid synthesis. Recombinant human Hexokinase3, fused to His tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
1mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol
Antigen Species
Human
Gene Category
Signal Transduction
Domain
1-923aa
Species of Protein
Human
Manufacturer - Search Terms
Hexokinase3, HK3, Hexokinase 3, EC 2.7.1.1, Hexokinase type III, HK III, Hexokinase-3, HKIII, Hexokinase3, HK3, HXK3., HXK0701-10ug, HXK0701-20ug, HXK0701-50ug, HXK0701-100ug, HXK0701-250ug, HXK0701-500ug, HXK0701-1mg, HXK0701-10, HXK0701-20, HXK0701-50, HXK0701-100, HXK0701-250, HXK0701-500, HXK0701-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 20 ug
Lieferbar: In stock
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