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Recombinant human IL-1 beta/IL1B protein

ArtNr NKM-ILB0701-500ug
Hersteller NKMAX
Menge 500 ug
Quantity options 100 ug 10 ug 20 ug 250 ug 500 ug 50 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag Untagged
Purity > 95% by SDS-PAGE
Sequence MAPVRSLNCT LRDSQQKSLV MSGPYELKAL HLQGQDMEQQ VVFSMSFVQG EESNDKIPVA LGLKEKNLYL SCVLKDDKPT LQLESVDPKN YPKKKMEKRF VFNKIEINNK LEFESAQFPN WYISTSQAEN MPVFLGGTKG GQDITDFTMQ FVSS
Citations Allan SM., et al. (2005), Nat. Rev. Immunol. 5:629.
Michaud DS., et al. (2006), Cancer Res.66(8):4525-30

Choi DY, et al. Molecularly imprinted polymer-based electrochemical impedimetric sensors on screen-printed carbon electrodes for the detection of trace cytokine IL-1β. (Biosens Bioelectron. 2022){https://pubmed.ncbi.nlm.nih.gov/35144170/}
Park RW, et al. Mobile Point-of-Care Device Using Molecularly Imprinted Polymer-Based Chemosensors Targeting Interleukin-1β Biomarker. (Biosensors. 2023){https://pubmed.ncbi.nlm.nih.gov/38131773/}
NCBI NP_000567.1
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Interleukin-1 beta,IL-1 beta,Catabolin,IL1F2
Similar products IL1F2, IL1 b, ILB0701-10ug, ILB0701-20ug, ILB0701-50ug, ILB0701-100ug, ILB0701-250ug, ILB0701-500ug, ILB0701-1mg, ILB0701-10, ILB0701-20, ILB0701-50, ILB0701-100, ILB0701-250, ILB0701-500, ILB0701-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Manufacturer - Applications
SDS-PAGE, Bioactivity
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
17 kDa (154aa) confirmed by MALDI-TOF
Description
Interleukin-1 (IL-1) has been considered a potentially important inflammatory mediator. It is composed of two distinct proteins, called as IL-1alpha and IL-1beta. IL-1beta is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1alpha and IL-1beta bind to the same receptor and they are structurally related polypeptides that share approximately 20% amino acid. Recombinant human IL-1beta was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
1mg/ml (determined by BCA assay)
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4)
Antigen Species
Human
Gene Category
Hormones & Cytokines
Domain
117-269aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment Only
Measured in a cell proliferation assay using D10.G4.1 mouse helper T cells. The ED50 range ≤ 12pg/ml.
Species of Protein
Human
Manufacturer - Search Terms
IL1 b, IL1F2, ILB0701-10ug, ILB0701-20ug, ILB0701-50ug, ILB0701-100ug, ILB0701-250ug, ILB0701-500ug, ILB0701-1mg, ILB0701-10, ILB0701-20, ILB0701-50, ILB0701-100, ILB0701-250, ILB0701-500, ILB0701-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 500 ug
Lieferbar: In stock
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