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Recombinant human IL-4 protein

ArtNr NKM-ILD0905-10ug
Hersteller NKMAX
Menge 10 ug
Quantity options 10 ug 250 ug 50 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 95% by SDS-PAGE
Sequence <MGSSHHHHHH SSGLVPRGSH> MHKCDITLQE IIKTLNSLTE QKTLCTELTV TDIFAASKNT TEKETFCRAA TVLRQFYSHH EKDTRCLGAT AQQFHRHKQL IRFLKRLDRN LWGLAGLNSC PVKEANQSTL ENFLERLKTI MREKYSKCSS
Citations Van Kimmenade A., et al. (1988) Eur J Biochem. 173(1):109-14.
Yokota T., et al. (1986) Proc. Natl. Acad. Sci. uSA. 83(16):5894-8.

Lee HM, et al. A comparative study of the effects of inhibitory cytokines on human natural killer cells and the mechanistic features of transforming growth factor-beta. (Cell Immunol. 2014){https://pubmed.ncbi.nlm.nih.gov/24879062/}
NCBI NP_000580
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Pitrakinra,MGC79402,Lymphocyte stimulatory factor 1,Interleukin-4 isoform 1,Interleukin 4,IL-4,BSF1,Binetrakin,BCGF1,B-cell stimulatory factor 1,B-cell growth factor 1,BCDF
Similar products IL-4, IL4, Interleukin-4, Interleukin 4, IL 4, B-cell stimulatory factor 1, BSF-1, Binetrakin, Lymphocyte stimulatory factor 1, Pitrakinra, B-cell growth factor 1, BCGF-1, BCGF1, BSF1, MGC79402, B cell growth factor 1, BCGF 1, BSF 1, Interleukin4, B cell stimulatory factor 1, BCDF, Pitrakinara, Interleukin-4 isoform 1, Interleukin 4 isoform 1, ILD0905-10ug, ILD0905-20ug, ILD0905-50ug, ILD0905-100ug, ILD0905-250ug, ILD0905-500ug, ILD0905-1mg, ILD0905-010, ILD0905-020, ILD0905-050, ILD0905-100, ILD0905-250, ILD0905-500, ILD0905-01M
Lieferbar
Manufacturer - Type
Recombinant Protein
Manufacturer - Applications
SDS-PAGE, Bioactivity
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
17.2 kDa (150aa) confirmed by MALDI-TOF
Description
Interleukin-4 (IL-4) is a pleiotropic cytokine that has many biological roles, including the stimulation of activated B-cell and T-cell proliferation, and the differentiation of naive helper T-cell to Th2 cells. Interleukin-4 is a co-stimulator of DNA-synthesis and is induces the expression of class II MHC molecules on resting B-cells. It also enhances both secretion and cell surface expression of IgE and IgG1. Recombinant Interleukin-4 protein, fused to His-tag at N-terminus, was expressed in E. coli and was purified by conventional chromatography techniques, after refolding of the isolated inclusion bodies in a renaturation buffer.
Concentration
0.5mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol
Antigen Species
Human
Gene Category
Hormones & Cytokines
Domain
25-153aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment Only
The ED50 for this effect is less or equal to 0.5ng/ml. Measured in a cell proliferation assay using TF1 human erythroleukemic cells.
Species of Protein
Human
Manufacturer - Search Terms
Pitrakinra, Pitrakinara, MGC79402, Lymphocyte stimulatory factor 1, Interleukin-4 isoform 1, Interleukin-4, Interleukin4, Interleukin 4 isoform 1, Interleukin 4, IL-4, IL4, IL 4, BSF-1, BSF1, BSF 1, Binetrakin, BCGF-1, BCGF1, BCGF 1, B-cell stimulatory factor 1, B-cell growth factor 1, BCDF, B cell stimulatory factor 1, B cell growth factor 1, ILD0905-10ug, ILD0905-20ug, ILD0905-50ug, ILD0905-100ug, ILD0905-250ug, ILD0905-500ug, ILD0905-1mg, ILD0905-010, ILD0905-020, ILD0905-050, ILD0905-100, ILD0905-250, ILD0905-500, ILD0905-01M

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 10 ug
Lieferbar: In stock
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