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Recombinant mouse Leptin/OB protein

ArtNr NKM-LEP0701-20ug
Hersteller NKMAX
Menge 20 ug
Quantity options 100 ug 20 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Mouse (Murine, Mus musculus)
Host E.coli
Konjugat/Tag Untagged
Purity > 95% by SDS-PAGE
Sequence MVPIQKVQDD TKTLIKTIVT RINDISHTQS VSAKQRVTGL DFIPGLHPIL SLSKMDQTLA VYQQVLTSLP SQNVLQIAND LENLRDLLHL LAFSKSCSLP QTSGLQKPES LDGVLEASLY STEVVALSRL QGSLQDILQQ LDVSPEC
Citations Jeong KJ., et al. (1999) Appl Environ Microbiol. 65(7), 3027-32.
Anini Y., et al. (2003) Diabetes. 52(2), 252-259.
Hyogo H., et al. (2002) J. Biol. Chem. 277(37), 34117-34124.
NCBI NP_032519
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias LEP,OB,OBS,Leptin Mouse,Obesity factor,Obese protein,Leptin
Similar products Leptin, LEP, OB, OBS, Obese protein, Obesity factor, Leptin Mouse, LEP0701-10ug, LEP0701-20ug, LEP0701-50ug, LEP0701-100ug, LEP0701-250ug, LEP0701-500ug, LEP0701-1mg, LEP0701-10, LEP0701-20, LEP0701-50, LEP0701-100, LEP0701-250, LEP0701-500, LEP0701-1
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Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
16 kDa (147aa) confirmed by MALDI-TOF
Description
Leptin is a 16-kDa nonglycosylated hormone that is produced in mature adipocytes. Leptin acts primarily in the hypothalamus to reduce food intake and body weight. In ob/ob mice, the gene encoding leptin is mutated, resulting in morbid obesity and associated abnormalities, including hyperphagia, hypothermia, diabetes and infertility. Originally discovered in the mouse, the cDNA for leptin has been so far cloned from a variety of species including human, rat, cow, chicken, pig, sheep and dog. Recombinant mouse leptin was overexpressed as insoluble protein aggregate in E. coli and purified by FPLC gel-filtration chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer
Concentration
1mg/ml (determined by Bradford assay)
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4)
Antigen Species
Mouse
Gene Category
Hormones & Cytokines
Domain
22-167aa
Species of Protein
Mouse
Manufacturer - Search Terms
Leptin, OB, LEP, OB, OBS, Leptin Mouse, Obesity factor, Obese protein, Leptin, LEP0701-10ug, LEP0701-20ug, LEP0701-50ug, LEP0701-100ug, LEP0701-250ug, LEP0701-500ug, LEP0701-1mg, LEP0701-10, LEP0701-20, LEP0701-50, LEP0701-100, LEP0701-250, LEP0701-500, LEP0701-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 20 ug
Lieferbar: In stock
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