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Recombinant human Serpin E1/PAI-1 protein

ArtNr NKM-PAI0701-20ug
Hersteller NKMAX
Menge 20 ug
Quantity options 100 ug 20 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 95% by SDS-PAGE
Sequence MGSSHHHHHH SSGLVPRGSH MVHHPPSYVA HLASDFGVRV FQQVAQASKD RNVVFSPYGV ASVLAMLQLT TGGETQQQIQ AAMGFKIDDK GMAPALRHLY KELMGPWNKD EISTTDAIFV QRDLKLVQGF MPHFFRLFRS TVKQVDFSEV ERARFIINDW VKTHTKGMIS NLLGKGAVDQ LTRLVLVNAL YFNGQWKTPF PDSSTHRRLF HKSDGSTVSV PMMAQTNKFN YT
Citations Gorlatova NV., et al.(2007) J Biol Chem. 282(12):9288-96.
Renckens R., et al. (2006) J Immunol. 177(11):8171-6.

Cho KS, et al. Valproic acid induces astrocyte-dependent neurite outgrowth from cultured rat primary cortical neuron via modulation of tPA/PAI-1 activity. (Glia. 2013){https://pubmed.ncbi.nlm.nih.gov/23378038/}
NCBI NP_000593
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Plasminogen activator inhibitor-1,PLANH1,SERPINE1,PAI1,PLANH1,Plasminogen activator inhibitor-1,Plasminogen activator inhibitor-1
Similar products SERPINE1, PAI1, PLANH1, Serpin E1, Plasminogen activator inhibitor-1, PAI0701-10ug, PAI0701-20ug, PAI0701-50ug, PAI0701-100ug, PAI0701-250ug, PAI0701-500ug, PAI0701-1mg, PAI0701-10, PAI0701-20, PAI0701-50, PAI0701-100, PAI0701-250, PAI0701-500, PAI0701-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Manufacturer - Applications
SDS-PAGE, Enzyme Activity
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
45 kDa (400aa)
Description
Plasminogen activator inhibitor-1 (PAI-1), a member of the serine protease inhibitor (serpin) super family. PAI-1 is the principal inhibitor of tissue plasminogen activator and urokinase, the activators of plasminogen and hence fibrinolysis. PAI-1 is mainly produced by the endothelium but is also secreted by other tissue types, such as adipose tissue. Recombinant human PAI-1, fused to His tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
1mg/ml (determined by Bradford assay)
Formulation
Liquid in. 50mM NaAc (pH 5.5) containing 10% glycerol, 0.1M NaCl
Antigen Species
Human
Gene Category
Enzymes & Proteases
Domain
24-402aa
Bioactivity Comment Only
The IC50 for this effect is less than 3 nM, Measured by its ability to inhibit uPA cleavage of the substrate Z-GGR-AMC.
Species of Protein
Human
Manufacturer - Search Terms
Serpin E1, PAI1, Plasminogen activator inhibitor-1, PLANH1, SERPINE1, PAI1, PLANH1, Plasminogen activator inhibitor-1, Plasminogen activator inhibitor-1, PAI0701-10ug, PAI0701-20ug, PAI0701-50ug, PAI0701-100ug, PAI0701-250ug, PAI0701-500ug, PAI0701-1mg, PAI0701-10, PAI0701-20, PAI0701-50, PAI0701-100, PAI0701-250, PAI0701-500, PAI0701-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 20 ug
Lieferbar: In stock
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