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Recombinant human c-kit Ligand/SCF protein

ArtNr NKM-SCF0601-500ug
Hersteller NKMAX
Menge 500 ug
Quantity options 100 ug 20 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag Untagged
Purity > 95% by SDS-PAGE
Sequence MEGICRNRVT NNVKDVTKLV ANLPKDYMIT LKYVPGMDVL PSHCWISEMV VQLSDSLTDL LDKFSNISEG LSNYSIIDKL VNIVDDLVEC VKENSSKDLK KSFKSPEPRL FTPEEFFRIF NRSIDAFKDF VVASETSDCV VSSTLSPEKD SRVSVTKPFM LPPVA
Citations Zhang Z., et al. (2000). Proc. Natl. Acad. Sci. u.S.A. 97, 7732.
Okada S , et al. (1992). Nippon Rinsho , 50, 1872.

Lee SH, et al. Involvement of MITF-A, an alternative isoform of mi transcription factor, on the expression of tryptase gene in human mast cells. (Exp Mol Med. 2010){https://pubmed.ncbi.nlm.nih.gov/20513998/}
Takahashi M, et al. CD133 is a positive marker for a distinct class of primitive human cord blood-derived CD34-negative hematopoietic stem cells. (Leukemia. 2014){https://pubmed.ncbi.nlm.nih.gov/24189293/}
Yamada T, et al. CXCL12 regulates differentiation of human immature melanocyte precursors as well as their migration. (Arch Dermatol Res. 2019){https://pubmed.ncbi.nlm.nih.gov/30483878/}
NCBI NP_000890.1
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Kit ligand,KITLG,Mast cell growth factor,MGF,Stem cell factor,SCF,c-Kit ligand,steel factor,SF,Kitl,KL-1,Familial progressive hyperpigmentation 2,FPH2,SLF,DFNA69
Similar products SCF, KITLG, MGF, Kitl, Kit ligand, C-kit ligand, Stem cell factor, Mast cell growth factor, SF, FPH2, KL-1, familial progressive hyperpigmentation 2, steel factor, SCF0601-10ug, SCF0601-20ug, SCF0601-50ug, SCF0601-100ug, SCF0601-250ug, SCF0601-500ug, SCF0601-1mg, SCF0601-10, SCF0601-20, SCF0601-50, SCF0601-100, SCF0601-250, SCF0601-500, SCF0601-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
18.5 kDa (165aa) confirmed by MALDI-TOF
Description
Stem Cell Factor (SCF) is a glycoprotein that plays a key role in hematopoiesis acting both as a positive and negative regulator, often in synergy with other cytokines. SCF binds to and activates the SCF receptor (SCFR), a receptor tyrosine kinase. SCF stimulates the proliferation of mast cells and is able to augment the proliferation of both myeloid and lymphoid hematopoietic progenitors in bone marrow culture. It also mediates cell-cell adhesion and acts synergistically with other cytokine. Recombinant human SCF was expressed in E. coli and purified by conventional column chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.
Concentration
1mg/ml (determined by Bradford assay)
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4)
Antigen Species
Human
Gene Category
Hormones & Cytokines
Domain
26-189aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Species of Protein
Human
Manufacturer - Search Terms
SCF, Stem cell factor, KITLG, MGF, SCF, C-kit ligand, Stem cell factor, SCF, Mast cell growth factor, MGF, Kit ligand, Stem cell factor, SF, Kitl, KL-1, FPH2, steel factor, familial progressive hyperpigmentation 2, SCF0601-10ug, SCF0601-20ug, SCF0601-50ug, SCF0601-100ug, SCF0601-250ug, SCF0601-500ug, SCF0601-1mg, SCF0601-10, SCF0601-20, SCF0601-50, SCF0601-100, SCF0601-250, SCF0601-500, SCF0601-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 500 ug
Lieferbar: In stock
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