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Recombinant human alpha-Synuclein (1-60aa) protein

ArtNr NKM-SNA3009-500ug
Hersteller NKMAX
Menge 500 ug
Quantity options 100 ug 20 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag Untagged
Purity > 95% by SDS-PAGE
Sequence MDVFMKGLSK AKEGVVAAAE KTKQGVAEAA GKTKEGVLYV GSKTKEGVVH GVATVAEKTK
Citations ueda., et al. (1993) Proc. Natl. Acad. Sci. 90(23):11282-6.
Jakes., et al. (1994) FEBS Letters 345, 27-32.

Kim EJ, et al. Dyrk1A phosphorylates alpha-synuclein and enhances intracellular inclusion formation. (J Biol Chem. 2006){https://pubmed.ncbi.nlm.nih.gov/16959772/}
Park JY, et al. Microglial phagocytosis is enhanced by monomeric alpha-synuclein, not aggregated alpha-synuclein: implications for Parkinsons disease. (Glia. 2008){https://pubmed.ncbi.nlm.nih.gov/18449945/}
Fantini J, et al. The fusogenic tilted peptide (67-78) of α-synuclein is a cholesterol binding domain. (Biochim Biophys Acta. 2011){https://pubmed.ncbi.nlm.nih.gov/21756873/}
Kawakami F, et al. Stimulatory effect of α-synuclein on the tau-phosphorylation by GSK-3β. (FEBS J. 2011){https://pubmed.ncbi.nlm.nih.gov/21985244/}
NCBI NP_000336.1
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias SNCA,NACP,PARK1,PARK4,PD1,α-synuclein Non-A beta component of AD amyloid,Non-A4 component of amyloid precursor,Parkinson disease 4,autosomal dominant Lewy body
Similar products Alpha synuclein, alpha-Synuclein, SNCA, NACP, PARK1, Non-A beta component of AD amyloid, Non-A4 component of amyloid precursor, PD1, MGC110988, PARK4, Synuclein alpha, alphaSYN, MGC105443, MGC127560, MGC64356, Non A beta component of AD amyloid, Non A4 component of amyloid precursor, Non-A-beta component of alzheimers disease amyloid, PARK 4, Parkinson disease familial 1, PD 1, Alpha-synuclein isoform NACP140, precursor of PARK 1, a-Synuclein (160aa), SNA3009-10ug, SNA3009-20ug, SNA3009-50ug, SNA3009-100ug, SNA3009-250ug, SNA3009-500ug, SNA3009-1mg, SNA3009-10, SNA3009-20, SNA3009-50, SNA3009-100, SNA3009-250, SNA3009-500, SNA3009-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
6.1 kDa (60aa) confirmed by MALDI-TOF
Description
A deletion mutant of alpha-synuclein (amino acids 1-60), which contains the N-terminal amphipathic domain. alpha-Syn 1-60 was overexpressed in E. coli and the recombinant protein was purified to apparent homogeneity by using conventional column chromatography techniques.
Concentration
1mg/ml (determined by BCA assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 7.5) containing 0.1M NaCl
Antigen Species
Human
Gene Category
Neuroscience
Domain
1-60aa
Species of Protein
Human
Manufacturer - Search Terms
a-Synuclein (160aa), SNCA, NACP, PARK1, alpha-Synuclein, Non-A beta component of AD amyloid, Non-A4 component of amyloid precursor, Alpha synuclein, Alpha-synuclein isoform NACP140, alphaSYN, MGC105443, MGC110988, MGC127560, MGC64356, Non A beta component of AD amyloid, Non A4 component of amyloid precursor, Non-A-beta component of alzheimers disease amyloid, precursor of PARK 1, PARK 4, PARK4, Parkinson disease familial 1, PD 1, PD1, Synuclein alpha, SNA3009-10ug, SNA3009-20ug, SNA3009-50ug, SNA3009-100ug, SNA3009-250ug, SNA3009-500ug, SNA3009-1mg, SNA3009-10, SNA3009-20, SNA3009-50, SNA3009-100, SNA3009-250, SNA3009-500, SNA3009-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 500 ug
Lieferbar: In stock
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