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Recombinant human alpha-Synuclein E46K protein

Recombinant human alpha-Synuclein E46K protein

ArtNr	NKM-SNA4001-20ug
Hersteller	NKMAX
Menge	20 ug
Quantity options	100 ug 20 ug 500 ug
Kategorie	Oncology Neuroscience Neuroinflammation Neural Mitochondrial Function Molecular Targets for Neuroscience Aging & Neurological Disorders Protein Aggregation, Clearance & Misfolding Infectious Diseases Viral Infections Coronavirus (COVID-19) By Cell Type Peptides & Proteins Recombinant Proteins Cell Biology Cell Status Adenocarcinoma Autophagy SDS-PAGE
Typ	Proteins Recombinant
Format	Liquid
Applikationen	SDS-PAGE
Specific against	Human (Homo sapiens)
Host	E.coli
Konjugat/Tag	Untagged
Purity	> 95% by SDS-PAGE
Sequence	MDVFMKGLSK AKEGVVAAAE KTKQGVAEAA GKTKEGVLYV GSKTKKGVVH GVATVAEKTK EQVTNVGGAV VTGVTAVAQK TVEGAGSIAA ATGFVKKDQL GKNEEGAPQE GILEDMPVDP DNEAYEMPSE EGYQDYEPEA
Citations	Juan J.Zarranz, . (2004) Ann. Neurol. 55, 164-173. Park JY, et al. Microglial phagocytosis is enhanced by monomeric alpha-synuclein, not aggregated alpha-synuclein: implications for Parkinsons disease. (Glia. 2008){https://pubmed.ncbi.nlm.nih.gov/18449945/} Kim KS, et al. Proteolytic cleavage of extracellular α-synuclein by plasmin: implications for Parkinson disease. (J Biol Chem. 2012){https://pubmed.ncbi.nlm.nih.gov/22619171/}
NCBI	NP_000336.1
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	SNCA,NACP,PARK1,PARK4,PD1,α-synuclein Non-A beta component of AD amyloid,Non-A4 component of amyloid precursor,Parkinson disease 4,autosomal dominant Lewy body
Similar products	Alpha synuclein, alpha-Synuclein, SNCA, NACP, PARK1, Non-A beta component of AD amyloid, Non-A4 component of amyloid precursor, PD1, MGC110988, PARK4, Synuclein alpha, alphaSYN, MGC105443, MGC127560, MGC64356, Non A beta component of AD amyloid, Non A4 component of amyloid precursor, Non-A-beta component of alzheimers disease amyloid, PARK 4, Parkinson disease familial 1, PD 1, Alpha-synuclein isoform NACP140, precursor of PARK 1, a-Synuclein E46K, alpha synuclein E46k, alpha-synuclein e46k, SNA4001-10ug, SNA4001-20ug, SNA4001-50ug, SNA4001-100ug, SNA4001-250ug, SNA4001-500ug, SNA4001-1mg, SNA4001-10, SNA4001-20, SNA4001-50, SNA4001-100, SNA4001-250, SNA4001-500, SNA4001-1
Lieferbar
Manufacturer - Type	Recombinant Protein
Storage Conditions	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight	14.4 (140aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
Description	alpha-Synuclein E46K is a mutant form of alpha-synuclein which is changed at position 46 from glutamate (E) to lysine (K). Recent studies have shown that this mutant (E46K) of alpha-synuclein causes Parkinson and Lewy Body dementia (DLB). alpha-Synuclein E46K was overexpressed in E. coli and purified to apparent homogeneity by using conventional column chromatography techniques
Concentration	1mg/ml (determined by BCA assay)
Formulation	Liquid in. 20mM Tris-HCl buffer (pH 7.5) containing 0.1M NaCl
Antigen Species	Human
Gene Category	Neuroscience
Domain	1-140aa
Species of Protein	Human
Manufacturer - Search Terms	a-Synuclein E46K, SNCA, NACP, PARK1, alpha-Synuclein, alpha synuclein E46k, alpha-synuclein e46k, Non-A beta component of AD amyloid, Non-A4 component of amyloid precursor, Alpha synuclein, Alpha-synuclein isoform NACP140, alphaSYN, MGC105443, MGC110988, MGC127560, MGC64356, Non A beta component of AD amyloid, Non A4 component of amyloid precursor, Non-A-beta component of alzheimers disease amyloid, precursor of PARK 1, PARK 4, PARK4, Parkinson disease familial 1, PD 1, PD1, Synuclein alpha, SNA4001-10ug, SNA4001-20ug, SNA4001-50ug, SNA4001-100ug, SNA4001-250ug, SNA4001-500ug, SNA4001-1mg, SNA4001-10, SNA4001-20, SNA4001-50, SNA4001-100, SNA4001-250, SNA4001-500, SNA4001-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 20 ug

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Lieferung vsl. bis 31.07.2025

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