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Recombinant human gamma-Synuclein protein

ArtNr NKM-SNG2001-20ug
Hersteller NKMAX
Menge 20 ug
Quantity options 100 ug 20 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag Untagged
Purity > 90% by SDS-PAGE
Sequence MDVFKKGFSI AKEGVVGAVE KTKQGVTEAA EKTKEGVMYV GAKTKENVVQ SVTSVAEKTK EQANAVSEAV VSSVNTVATK TVEEAENIAV TSGVVRKEDL RPSAPQQEGV ASKEKEEVAE EAQSGGD
Citations Ji H., et al. (1997) Cancer Res. 57(4):759-64.
Ahn KJ, et al. Amino acid sequence motifs and mechanistic features of the membrane translocation of alpha-synuclein. (J Neurochem. 2006)
Park JY, et al. Microglial phagocytosis is enhanced by monomeric alpha-synuclein, not aggregated alpha-synuclein: implications for Parkinsons disease. (Glia. 2008)
Kim KS, et al. Regulation of Weibel-Palade body exocytosis by alpha-synuclein in endothelial cells. (J Biol Chem. 2010)
Kawakami F, et al. Stimulatory effect of α-synuclein on the tau-phosphorylation by GSK-3β. (FEBS J. 2011)
Konno M, et al. Suppression of dynamin GTPase decreases α-synuclein uptake by neuronal and oligodendroglial cells: a potent therapeutic target for synucleinopathy. (Mol Neurodegener. 2012)
Førland MG, et al. Validation of a new assay for α-synuclein detection in cerebrospinal fluid. (Clin Chem Lab Med. 2017)
NCBI NP_003078.2
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Synuclein gamma,SNCG,BCSG1,SR,Persyn,PRSN,Synoretin,Breast cancer-specific gene 1,ɣ-synuclein
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Manufacturer - Type
Proteins
Manufacturer - Category
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
13.3 kDa (127aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
Description
gamma-synuclein (Originally known as a breast cancer specific gene product, BCSG1) is an acidic neuronal protein of 127 amino acids. The protein coding region of gamma-synuclein was amplified by RT-PCR and cloned into an E. coli expression vector. gamma-synuclein was overexpressed in E. coli and purified to apparent homogeneity by taking advantage of the thermosolubility of the protein and by using conventional column chromatography techniques.
Concentration
1mg/ml (determined by BCA assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 7.5) containing 0.1M NaCl
Antigen Species
Human
Gene Category
Neuroscience
Domain
1-127aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Species of Protein
Human
Manufacturer - Search Terms
g-Synuclein, Synuclein gamma (breast cancer-specific protein 1), SNCG, BCSG1, PERSYN, PRSN, gamma-Synuclein, Persyn, Breast cancer-specific gene 1 protein, Synoretin, SR, gamma-synuclein, gamma synuclein, Synuclein, gamma (breast cancer-specific protein 1) BCSG 1, Breast cancer specific gene 1, Breast cancer specific gene 1 protein, Breast cancer specific protein 1, Gamma synuclein, SNCG protein, SR, Synuclein gamma, SNG2001-10ug, SNG2001-20ug, SNG2001-50ug, SNG2001-100ug, SNG2001-250ug, SNG2001-500ug, SNG2001-1mg, SNG2001-10, SNG2001-20, SNG2001-50, SNG2001-100, SNG2001-250, SNG2001-500, SNG2001-1
Manufacturer - Similar Names
g-Synuclein, Synuclein gamma (breast cancer-specific protein 1), SNCG, BCSG1, PERSYN, PRSN, gamma-Synuclein, Persyn, Breast cancer-specific gene 1 protein, Synoretin, SR, gamma-synuclein, gamma synuclein, Synuclein, gamma (breast cancer-specific protein 1) BCSG 1, Breast cancer specific gene 1, Breast cancer specific gene 1 protein, Breast cancer specific protein 1, Gamma synuclein, SNCG protein, SR, Synuclein gamma, SNG2001-10ug, SNG2001-20ug, SNG2001-50ug, SNG2001-100ug, SNG2001-250ug, SNG2001-500ug, SNG2001-1mg, SNG2001-10, SNG2001-20, SNG2001-50, SNG2001-100, SNG2001-250, SNG2001-500, SNG2001-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 20 ug
Lieferbar: In stock
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