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[Novoprotein] Recombinant Mouse Dickkopf-Related Protein 1/mDKK1/DKK-1 (N-8His)

ArtNr NOVP-C773-1mg
Hersteller Novoprotein Scientific
Menge 1 mg
Quantity options 10 ug 1 mg 500 ug 50 ug
Kategorie
Typ Proteins Recombinant
Format Lyophilized
Specific against Mouse (Murine, Mus musculus)
Host Human
Konjugat/Tag HIS
Purity Greater than 95% as determined by reducing SDS-PAGE.
Sequence HHHHHHHHQTLNSVLINSNAIKNLPPPLGGAGGQP GSAVSVAPGVLYEGGNKYQTLDNYQPYPCAEDEEC GSDEYCSSPSRGAAGVGGVQICLACRKRRKRCMRH AMCCPGNYCKNGICMPSDHSHFPRGEIEESIIENL GNDHNAAAGDGYPRRTTLTSKIYHTKGQEGSVCLR SSDCAAGLCCARHFWSKICKPVLKEGQVCTKHKRK GSHGLEIFQRCYCGEGLACRIQKDHHQASNSSRLH TCQ
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Dickkopf-related protein 1,Dickkopf-1,Dkk-1,mDkk-1,Dkk1
Versandbedingung Raumtemperatur
Lieferbar
Shipping Temperature
The product is shipped at ambient temperature.
Storage Conditions
Lyophilized protein should be stored at < -20C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20C for 3 months.
Molecular Weight
27, 4
Description
Recombinant Mouse Dickkopf-related protein 1 is produced by our Mammalian expression system & the target gene encoding Thr32-His272 is expressed with a 8His tag at the N-terminus.
Formulation
Lyophilized from a 0.2 um filtered solution of PBS, pH7.4.
Background
This gene encodes a protein that is a member of the dickkopf family. It possesses two clusters of ten cysteine residues separated by a linker region. The protein highly expressed in thyroid, small intestine, stomach, liver, placenta, pancreas, uterus, abdominal cavity, bladder & skin. Weaker expression has been detected in colon & spleen. It antagonizes canonical Wnt signaling by inhibiting LRP5/6interaction with Wnt & by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6.
Endotoxin
Less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Reconstitution
Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Sequence Length
Thr32-His272

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 1 mg
Lieferbar: In stock
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