Recombinant Human Ephrin B Receptor 1/EphB1 (C-Fc)

Lyophilized protein should be stored at < -20C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20C for 3 months.

Recombinant Human Ephrin B Receptor 1 is produced by our Mammalian expression system & the target gene encoding Met18-Pro540 is expressed with a Fc tag at the C-terminus.

Ephrin Type-B Receptor 1 (EPHB1) is a single-pass type I membrane protein that belongs to the Ephrin-B family of receptor tyrosine kinases involved in the development of embryonic nervous & vascular systems. EPHB1 contains two fibronectin type-III domains, one protein kinase domain & one Sterile Alpha Motif (SAM)domain. EPHB1 is able to stimulate fibroblast motility on extracellular matrix in a kinase-dependent manner, which is also correlated with its association with Grb7, an adaptor molecule implicated in the regulation of cell migration. It binds to Ephrin-B1, Ephrin-B2 & Ephrin-B3. EPHB1 plays an important roles in diverse biological processes including nervous system development, angiogenesis, & neural synapsis formation & maturation & may be involved in cell-cell interactions in the nervous system.

Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.