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[Novoprotein] Recombinant Human Cyclin-Dependent Kinase 6/CXK6 (N-6His)

ArtNr NOVP-CF11-10ug
Hersteller Novoprotein Scientific
Menge 10 ug
Quantity options 10 ug 1 mg 500 ug 50 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity Greater than 95% as determined by reducing SDS-PAGE.
Dry ice Yes
Sequence MGSSHHHHHHSSGLVPRGSHMEKDGLCRADQQYEC VAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTG EEGMPLSTIREVAVLRHLETFEHPNVVRLFDVCTV SRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTE TIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTS SGQIKLADFGLARIYSFQMALTSVVVTLWYRAPEV LLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDV DQL
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Cyclin-Dependent Kinase 6,Cell Division Protein Kinase 6,Serine/Threonine-Protein Kinase PLSTIRE,CDK6,CDKN6
Similar products CDK6
Lieferbar
Shipping Temperature
The product is shipped on dry ice/ice packs.
Storage Conditions
Store at < -20C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.
Molecular Weight
39, 1
Description
Recombinant Human Cyclin-Dependent Kinase 6 is produced by our E.coli expression system & the target gene encoding Met1-Ala326 is expressed with a 6His tag at the N-terminus.
Formulation
Supplied as a 0.2 um filtered solution of 50mM Tris, 100mM NaCl, 20% Glycerol, 5mM DTT, pH 8.0.
Background
Cyclin-Dependent Kinase 6 (CDK6 belongs to the CMGC Ser/Thr protein kinase family & CDC2/CDKX subfamily. CDK6 is expressed in many tissues & contains one protein kinase domain. This cyclin forms a complex with & functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. Mutations & overexpression of CDK6, which alters cell cycle progression, are observed frequently in a variety of tumors & may contribute to tumorigenesis.
Endotoxin
Less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Reconstitution
Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Sequence Length
Met1-Ala326

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 10 ug
Lieferbar: In stock
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