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HCoV-OC43 Nucleocapsid protein, His Tag Europäischer Partner

ArtNr NUN-V5145-1mg
Hersteller ACROBiosystems
Menge 200 ug x 5
Quantity options 100 ug 200 ug x 5
Kategorie
Typ Proteins Recombinant
Format Solid
Specific against Coronavirus
Host E.coli
Konjugat/Tag Unconjugated, HIS
Purity 90%
Citations (1) Reuter M, et al. Virus Genes. 2018. 54(1):5-16.
(2) Grunewald ME, et al. Virology. 2018. 517:62-68.
(3) Jeeva S, et al. PLoS One. 2017. 12(9):e0184935.
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Nucleocapsid protein,NP,Protein N,COVID-19
Versandbedingung Raumtemperatur
Lieferbar
Specificity HCoV-OC43
Manufacturer - Category
Protein / Viral Proteins
Manufacturer - Conjugate / Tag
N-6xHis, Unconjugated
Shipping Temperature
RT
Storage Conditions
-20°C
Molecular Weight
50.3 kDa
Manufacturer - Format
Powder
Description
HCoV-OC43 Nucleocapsid, His Tag (NUN-V5145) is expressed from E. coli cells. It contains AA Met 1 - Ile 448 (Accession # P33469-1).
Background
Nucleocapsid (N) protein is the most abundant protein found in coronavirus. CoV N protein is a highly immunogenic phosphoprotein important for viral genome replication and modulation of cell signaling pathways. It was first identified by a research team while they were screening for ADP-ribosylated proteins during coronavirus (CoV) infection (Grunewald M. E., et al. 2017, Virology; 517: 62-68). The array of diverse functional activities accommodated in N protein makes it more than a structural protein but also an interesting target in the development of antiviral therapeutics. Because of the conservation of N protein sequence and its strong immunogenicity, N protein of coronavirus is chosen as a diagnostic tool.
Molecule
Nucleocapsid protein
Exp Region
Met 1 - Ile 448
Characteristics
This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 50.3 kDa. The protein migrates as 55 kDa under reducing (R) condition (SDS-PAGE).
Endotoxin
1.0 EU per μg
Buffer
40 mM PB, 500 mM NaCl, pH 7.4
Stability
● -20°C to -70°C for 12 months in lyophilized state;
● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant
trehalose

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 200 ug x 5
Lieferbar: In stock
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