Recombinant Human Galectin-9/LGALS9 (N-GST)

N-GST

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

60 kDa

Galectin-9 is a cytoplasmic protein that contains two galectin domains. Galectin-9 is an S-type lectin that is over-expressed in Hodgkin's disease tissue. Galectin-9 binds galactosides and has high affinity for the Forssman pentasaccharide. Galectin-9 plays a role in thymocyte-epithelial interactions relevant to the biology of the thymus and Inhibits cell proliferation. Galectin-9 is a ligand for HAVCR2/TIM3 and induces T-helper type 1 lymphocyte (Th1) death. In addition, Galectin-9 suppresses tumor cell metastasis by interfering with the associations CD44, VCAM-1, Integrin α4β1

< 1.0 EU per μg of the protein as determined by the LAL method.

Supplied as a 0.2 um filtered solution of 1M PBS, 100 mM GSH, 1% Tritonx-100, 15% Glycerol, pH 8.0.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.