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Recombinant Human Tumor-associated Calcium Signal Transducer 2/TROP-2 (248AA, C-6His)

Recombinant Human Tumor-associated Calcium Signal Transducer 2/TROP-2 (248AA, C-6His)

ArtNr	PKSH033991-50
Hersteller	Elabscience
Menge	50 ug
Quantity options	10 ug 50 ug
Kategorie	Oncology By Cell Type Carcinoma Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Format	Lyophilized Powder
Applikationen	Blocking
Specific against	Human (Homo sapiens)
Host	HEK293 cells
Konjugat/Tag	HIS
Purity	> 95 % as determined by reducing SDS-PAGE.
Sequence	His27-Thr274
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Cell surface glycoprotein Trop-2, Membrane component chromosome 1 surface marker 1, TACSTD2, TROP2, Tumor-associated calcium signal transducer 2
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Applications	BLI
Manufacturer - Category	Recombinant Proteins / Others
Manufacturer - Conjugate / Tag	C-His
Shipping Temperature	This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight	28.9 kDa
Observed Molecular Weight	40-50 kDa
Background	Tumor associated calcium signal transducer 2 (TACSTD2, TROP-2) is a type I cell surface glycoprotein that is highly expressed on human carcinomas. It was originally identified as an antigen present on human gastrointestinal tumors and is the second of two members of this family. Human and mouse TROP-2 share 87% amino acid (aa) similarity. TROP-2 is capable of transducing an intracellular calcium signal and may play a role in tumor growth. It also has adhesive functions.
Abbreviation	TROP-2
Endotoxin	< 1.0 EU per μg of the protein as determined by the LAL method.
Reconstitution	Please refer to the printed manual for detailed information.
Formulation	Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Activity	Loaded Anti-Human TROP-2 mAb-Fc on Protein A Biosensor, can bind Human TROP-2-His with an affinity constant of 0.21 nM as determined in BLI assay.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

PKSH033991-50-datasheet.pdf

PKSH033991-50-safety-datasheet.pdf