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Recombinant Human HLA-A*0201 NY-ESO-1 complex Protein (C-10His)

Recombinant Human HLA-A*0201 NY-ESO-1 complex Protein (C-10His)

ArtNr	PKSH034036-50
Hersteller	Elabscience
Menge	50 ug
Quantity options	10 ug 50 ug
Kategorie	Oncology By Cell Type Carcinoma Hematology Lymphoma Myeloma Melanoma Sarcoma Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Format	Lyophilized Powder
Specific against	Human (Homo sapiens)
Host	HEK293 cells
Konjugat/Tag	HIS
Purity	> 90 % as determined by reducing SDS-PAGE.
Sequence	SLLMWITQC&Ile21-Met119&Gly25-Ile308(Ala269Val)
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	HLA-A*0201 NY-ESO-1 complex Protein, MHC, MY-ESO-1
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Category	Recombinant Proteins / Others
Manufacturer - Conjugate / Tag	C-His
Shipping Temperature	This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight	49.1 kDa
Observed Molecular Weight	55-60 kDa
Research Areas	Microbiology, immunology, Cardiovascular, Cancer
Background	NY-ESO-1 is a well-known cancer-testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit spontaneous humoral and cellular immune responses, together with its restricted expression pattern, have rendered it a good candidate target for cancer immunotherapy. Optimally assembled peptide-HLA-B2M trimer translocates to the surface of antigen-presenting cells, where it interacts with TCR and CD8 coreceptor on the surface of T cells.
Abbreviation	HLA-A*0201 NY-ESO-1 complex
Endotoxin	< 1.0 EU per μg of the protein as determined by the LAL method.
Reconstitution	Please refer to the printed manual for detailed information.
Formulation	Lyophilized from a 0.2 um filtered solution of 20mM PB, 500mM NaCl, pH7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Activity	Not validated for activity

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

PKSH034036-50-datasheet.pdf

PKSH034036-50-safety-datasheet.pdf