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LIGHT Recombinant Protein

ArtNr PRS-40-301-0.015mg
Hersteller ProSci
Menge 0.015 mg
Quantity options 0.003 mg 0.015 mg
Kategorie
Typ Proteins Recombinant
Format Lyophilized
Specific against other
Purity Greater than 95% by SDS-PAGE gel and HPLC analyses.<br><br>Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Sequence RLGEMVTRLP DGPAGSWEQL IQERRSHEVN PAAHLTGANS SLTGSGGPLL WETQLGLAFL RGLSYHDGAL VVTKAGYYYI YSKVQLGGVG CPLGLASTIT HGLYKRTPRY PEELELLVSQ QSPCGRATSS SRVWWDSSFL GGVVHLEAGE KVVVRVLDER LVRLRDGTRS YFGAFMV
NCBI TNFSF14
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias LTg,TR2,CD258,HVEML,LIGHT,UNQ391/PRO726,Tumor necrosis factor ligand superfamily member 14,Herpes virus entry mediator ligand,HVEM-L
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Type
Recombinant Proteins
Shipping Temperature
Room Temp
Storage Conditions
The lyophilized LIGHT recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted LIGHT is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing LIGHT recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Background
LIGHT belongs to the TNF family of ligands, and can signal through the herpes virus entry mediator type A receptor (HVEM, TNFRSF14), LTβ R, or bind to a decoy receptor, DcR3. It is expressed in splenocytes, activated PBL, CD+8 tumor infiltrating lymphocytes, granulocytes, and monocytes. LIGHT has the ability to active NFκ B, to co-stimulate the activation of lymphocytes and to induce apoptosis in certain human tumor cells. Recombinant human LIGHT has a calculated mass of 19.3 kDa containing 177 amino acid residues. Due to glycosylation LIGHT migrates between 20.0-22.5 kDa by SDS-PAGE under non-reducing conditions.
By Type
Apoptosis, Chemokines & Cytokines, Immunology, Infectious Disease, Innate Immunity, Signal Transduction
Protein Gi #
25952144
NCBI Official Name
tumor necrosis factor (ligand) superfamily, member 14
NCBI Organism
Homo sapiens
Disclaimer
This product is for research use only.
Manufacturer - Species
Human
By Species
Human

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 0.015 mg
Lieferbar: In stock
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