4-1BB Ligand Recombinant Protein

Recombinant Proteins

The lyophilized 4-1BB Ligand recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted 4-1BB Ligand is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing 4-1BB Ligand recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

4-1BBL, a member of the TNF superfamily, is expressed in B cells, dendritic cells, activated T cells and macrophages. 4-1BBL binds to its receptor 4-1BB, and provides a co-stimulatory signal for T cell activation and expansion. The human 4-1BBL gene codes for a 254 amino acid type II transmembrane containing a 28 amino acid cytoplasmic domain, a 21 amino acid transmembrane domain, and a 205 amino acid extracellular domain. The soluble form of 4-1BBL contains the TNF-like portion of the extracellular domain of 4-1BBL. Recombinant human 4-1BBL is a soluble 19.5 kDa protein consisting of 185 amino acid residues.

4507609

Homo sapiens

Human