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IGF-BP7 Recombinant Protein

ArtNr PRS-40-321-0.005mg
Hersteller ProSci
Menge 0.005 mg
Quantity options 0.005 mg 0.025 mg
Kategorie
Typ Proteins Recombinant
Format Lyophilized
Specific against other
Purity Greater than 98% by SDS-PAGE gel and HPLC analyses.<br><br>Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Sequence MSSSDTCGPC EPASCPPLPP LGCLLGETRD ACGCCPMCAR GEGEPCGGGG AGRGYCAPGM ECVKSRKRRK GKAGAAAGGP GVSGVCVCKS RYPVCGSDGT TYPSGCQLRA ASQRAESRGE KAITQVSKGT CEQGPSIVTP PKDIWNVTGA QVYLSCEVIG IPTPVLIWNK VKRGHYGVQR TELLPGDRDN LAIQTRGGPE KHEVTGWVLV SPLSKEDAGE YECHASNSQG QA
NCBI IGFBP7
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias AGM,PSF,TAF,FSTL2,IBP-7,MAC25,IGFBP-7,RAMSVPS,IGFBP-7v,IGFBPRP1,Insulin-like growth factor-binding protein 7,IGFBP-rP1
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Type
Recombinant Proteins
Shipping Temperature
Room Temp
Storage Conditions
The lyophilized IGF-BP7 recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted IGF-BP7 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing IGF-BP7 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Background
IGF-BPs controls the distribution, function and activity of IGFs in various cell tissues and body fluids. Currently there are seven named IGF-BPs that form high affinity complexes with both IGF-I and IGF-II. IGF-BP7 is expressed in a wide range of normal human tissues and it generally shows reduced expression in cancer cell lines of prostate, breast, colon, and lung origin. It plays a role in skeletal myogenesis by binding to IGF in a manner that inhibits IGF induced differentiation of skeletal myoblasts, without affecting IGF induced proliferation. Additionally, IGF-BP7 suppresses growth and colony formation of prostate and breast cancer cell lines through an IGF independent mechanism, which causes a delay in the G1 phase of the cell cycle, and increased apoptosis. Recombinant human IGF-BP7 is a 26.4 kDa protein consisting of 257 amino acid residues.
By Type
Cancer
Protein Gi #
359465608
NCBI Official Name
insulin-like growth factor binding protein 7
NCBI Organism
Homo sapiens
Disclaimer
This product is for research use only.
Manufacturer - Species
Human
By Species
Human

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 0.005 mg
Lieferbar: In stock
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Lieferung vsl. bis 04.12.2025 

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