Vergleich

OX40 Recombinant Protein

ArtNr PRS-90-227-50ug
Hersteller ProSci
Menge 50 ug
Kategorie
Typ Proteins Recombinant
Format Lyophilized
Specific against other
Konjugat/Tag Fc
Purity >95% (SDS-PAGE).<br><br> Endotoxin level is less than 0.01EU/ μg purified protein (LAL test; Lonza).
Sequence Human OX40 (aa 29-214) is fused at the C-terminus to the Fc portion of human IgG1.
NCBI TNFRSF4
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias TNFRSF 4,Tumor Necrosis Factor Receptor Superfamily Member 4,CD134
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Type
Recombinant Proteins
Shipping Temperature
Room Temp
Storage Conditions
Stable for at least 6 months after receipt when stored at -20˚ C.
Biological Activity
Blocks T cell proliferation induced by CD134L.
Background
OX40 binds to receptors on T-cells, preventing them from dying and subsequently increasing cytokine production. OX40 has a critical role in the maintenance of an immune response. OX40:Fc was shown to prevent OX40 from reaching the T-cell receptors, thus reducing the T-cell response. Experiments in mice have demonstrated that OX40:Fc can reduce the symptoms associated with the cytokine storm (an immune overreaction) while allowing the immune system to fight off the virus successfully.
Protein Gi #
1171933
Concentration
1mg/ml after reconstitution.
Buffer
Contains PBS. Reconstitute with 50 μ l sterile water.
Application Note
This recombinant proteins is for research use only.
NCBI Official Name
tumor necrosis factor receptor superfamily member 4
NCBI Organism
Homo sapiens
Disclaimer
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.
Manufacturer - Species
Human, Mouse
By Species
Human, Mouse

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ug
Lieferbar: In stock
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