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OX40 Recombinant Protein

OX40 Recombinant Protein

Item no.	PRS-90-227-50ug
Manufacturer	ProSci
Amount	50 ug
Category	Oncology Neuroscience Neuroinflammation Metabolism Diabetes By Cell Type Carcinoma Peptides & Proteins Recombinant Proteins Cell Biology Obesity Cell Culture Cytokines Cell Status Necrosis Apoptosis
Type	Proteins Recombinant
Format	Lyophilized
Specific against	other
Conjugate/Tag	Fc
Purity	>95% (SDS-PAGE).<br><br> Endotoxin level is less than 0.01EU/ μg purified protein (LAL test; Lonza).
Sequence	Human OX40 (aa 29-214) is fused at the C-terminus to the Fc portion of human IgG1.
NCBI	TNFRSF4
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	TNFRSF 4,Tumor Necrosis Factor Receptor Superfamily Member 4,CD134
Shipping Condition	Room temperature
Available
Manufacturer - Type	Recombinant Proteins
Shipping Temperature	Room Temp
Storage Conditions	Stable for at least 6 months after receipt when stored at -20˚ C.
Biological Activity	Blocks T cell proliferation induced by CD134L.
Background	OX40 binds to receptors on T-cells, preventing them from dying and subsequently increasing cytokine production. OX40 has a critical role in the maintenance of an immune response. OX40:Fc was shown to prevent OX40 from reaching the T-cell receptors, thus reducing the T-cell response. Experiments in mice have demonstrated that OX40:Fc can reduce the symptoms associated with the cytokine storm (an immune overreaction) while allowing the immune system to fight off the virus successfully.
Protein Gi #	1171933
Concentration	1mg/ml after reconstitution.
Buffer	Contains PBS. Reconstitute with 50 μ l sterile water.
Application Note	This recombinant proteins is for research use only.
NCBI Official Name	tumor necrosis factor receptor superfamily member 4
NCBI Organism	Homo sapiens
Disclaimer	Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.
Manufacturer - Species	Human, Mouse
By Species	Human, Mouse

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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Delivery expected until 1/1/2026

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