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NAD Synthetase M. tuberculosis Recombinant Protein

ArtNr PRS-90-366-50ug
Hersteller ProSci
Menge 50 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Specific against other
Konjugat/Tag HIS
Purity >98% (SDS-PAGE)
Dry ice Yes
Sequence NAD synthetase (Mycobacterium tuberculosis) (with mutation S444A) is fused at the N-terminus to a His-tag.
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias NADE, Glutamine-dependent NAD(+) Synthetase, EC 6.3.5.1
Lieferbar
Manufacturer - Applications
This recombinant proteins is for research use only.
Storage Conditions
Stable for at least 6 months after receipt when stored at -80°C.
Biological Activity
~0.1 U/mg protein. (Ammonium or glutamine as nitrogen source). One unit is defined as the amount of enzyme that synthesizes 1umol NAD per min.
Background
NAD synthetase is an essential enzyme involved in both the de novo biosynthesis and salvage of NAD+, catalyzing the final step of both pathways. Since NAD has a vital role in cell metabolism, the enzyme represents a valid target for the development of new antimycobacterial agents. It can use both glutamine or ammonia as a nitrogen source. Catalytic activity: ATP + deamido-NAD+ + L-glutamine + H2O = AMP + diphosphate + NAD+ + L-glutamate
Concentration
0.5mg/ml (Lot specific)
Buffer
In 20mM TRIS-HCl, pH 7.8.
Disclaimer
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ug
Lieferbar: In stock
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