Comparison

NAD Synthetase M. tuberculosis Recombinant Protein

Item no. PRS-90-366-50ug
Manufacturer ProSci
Amount 50 ug
Category
Type Proteins Recombinant
Format Liquid
Specific against other
Conjugate/Tag HIS
Purity >98% (SDS-PAGE)
Dry ice Yes
Sequence NAD synthetase (Mycobacterium tuberculosis) (with mutation S444A) is fused at the N-terminus to a His-tag.
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias NADE, Glutamine-dependent NAD(+) Synthetase, EC 6.3.5.1
Available
Manufacturer - Applications
This recombinant proteins is for research use only.
Storage Conditions
Stable for at least 6 months after receipt when stored at -80°C.
Biological Activity
~0.1 U/mg protein. (Ammonium or glutamine as nitrogen source). One unit is defined as the amount of enzyme that synthesizes 1umol NAD per min.
Background
NAD synthetase is an essential enzyme involved in both the de novo biosynthesis and salvage of NAD+, catalyzing the final step of both pathways. Since NAD has a vital role in cell metabolism, the enzyme represents a valid target for the development of new antimycobacterial agents. It can use both glutamine or ammonia as a nitrogen source. Catalytic activity: ATP + deamido-NAD+ + L-glutamine + H2O = AMP + diphosphate + NAD+ + L-glutamate
Concentration
0.5mg/ml (Lot specific)
Buffer
In 20mM TRIS-HCl, pH 7.8.
Disclaimer
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 ug
Available: In stock
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