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IL-2 Recombinant Protein

ArtNr PRS-90-554-50ug
Hersteller ProSci
Menge 50 ug
Kategorie
Typ Proteins Recombinant
Format Lyophilized
Specific against other
Purity ≥95% (SDS-PAGE).<br><br> Endotoxin level is less than <0.01EU/μg protein (LAL test; Lonza).
Sequence The extracellular domain of human IL-2 (aa 21-153) with a N-terminal Met.
NCBI IL2
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Interleukin-2; Aldesleukin
Lieferbar
Manufacturer - Applications
This recombinant proteins is for research use only.
Storage Conditions
Stable for at least 1 year after receipt when stored at -80°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Molecular Weight
~14kDa (SDS-PAGE)
Biological Activity
Measured in a cell proliferation assay using CTLL2 cells. The ED50 for this effect is typically 0.35-1.4ng/ml.
Background
Interleukin-2 (IL-2) is a 133 amino acid glycoprotein with one intramolecular disulfide bond and variable glycosylation. It is secreted by activated T cells and induces proliferation and maturation of activated T cells, natural killer cells, and lymphokine activated killer cells. IL-2 also stimulates proliferation of antibody-producing B cells, activates neutrophils, and induces mononuclear cells to secrete IFN-gamma and TNF-alpha and -beta. Moreover, studies have shown that IL-2 is required for activation-induced apoptosis, an important hemeostatic mechanism in the immune system, which is involved in the maintenance of peripheral tolerance to self-antigens.
Concentration
0.5mg/ml
Buffer
Lyophilized from sterile 0.1% TFA, 70% acetonitrile.
NCBI Official Name
interleukin 2
NCBI Organism
Homo sapiens
Disclaimer
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ug
Lieferbar: In stock
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