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IL-2 Recombinant Protein

IL-2 Recombinant Protein

Manufacturer	ProSci
Category	Peptides & Proteins Recombinant Proteins Cell Biology Cell Culture Cytokines Immunostaining
Type	Proteins Recombinant
Specific against	other
Format	Lyophilized
Amount	50 ug
Item no.	PRS-90-554-50ug
eClass 6.1	34160400
eClass 9.0	42020190
Available
Applications	This recombinant proteins is for research use only.
Applications	This recombinant proteins is for research use only.
Buffer	Lyophilized from sterile 0.1% TFA, 70% acetonitrile.
Storage Conditions	Stable for at least 1 year after receipt when stored at -80˚ C. Working aliquots are stable for up to 3 months when stored at -20˚ C.
Disclaimer	Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.
Predicted Molecular Weight	~14kDa (SDS-PAGE)
Purity	≥95% (SDS-PAGE). Endotoxin level is less than <0.01EU/μg protein (LAL test; Lonza).
Background	Interleukin-2 (IL-2) is a 133 amino acid glycoprotein with one intramolecular disulfide bond and variable glycosylation. It is secreted by activated T cells and induces proliferation and maturation of activated T cells, natural killer cells, and lymphokine activated killer cells. IL-2 also stimulates proliferation of antibody-producing B cells, activates neutrophils, and induces mononuclear cells to secrete IFN-gamma and TNF-alpha and -beta. Moreover, studies have shown that IL-2 is required for activation-induced apoptosis, an important hemeostatic mechanism in the immune system, which is involved in the maintenance of peripheral tolerance to self-antigens.
Concentration	0.5mg/ml
Accession #	NP_000577.2
Ncbi Gene Id #	3558
Ncbi Official Symbol	IL2
Ncbi Official Full Name	interleukin 2
Ncbi Organism	Homo sapiens
Sequence	The extracellular domain of human IL-2 (aa 21-153) with a N-terminal Met.
Biological Activity	Measured in a cell proliferation assay using CTLL2 cells. The ED50 for this effect is typically 0.35-1.4ng/ml.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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Delivery expected until 6/6/2024