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IL-10 Recombinant Protein

ArtNr PRS-90-555-10ug
Hersteller ProSci
Menge 10 ug
Kategorie
Typ Proteins Recombinant
Format Lyophilized
Specific against other
Purity ≥95% (SDS-PAGE).<br><br> Endotoxin level is less than <0.01EU/μg protein (LAL test; Lonza).
Sequence Human IL-10 (aa 19-178) with a N-terminal Met.
NCBI IL10
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Interleukin-10; Cytokine Synthesis Inhibitory Factor; CSIF
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Manufacturer - Applications
This recombinant proteins is for research use only.
Storage Conditions
Stable for at least 1 year after receipt when stored at -80°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Molecular Weight
~18kDa (SDS-PAGE)
Biological Activity
Immobilized human IL-10 at 10ug/ml (100ul/well) can bind Cynomolgus IL-10RA-Fc. The EC50 of Cynomolgus IL-10RA-Fc is 0.24-0.56ug/ml.
Background
Interleukin-10 (IL-10) is a cytokine produced by activated Th2 cells, B cells, keratinocytes and monocytes/macrophages. In vitro murine and human IL-10 inhibits cytokine synthesis by Th1 cells, natural killer cells and monocytes/macrophages. Several studies have suggested the potential application of IL-10 as an anti-inflammatory agent in the treatment of septic shock and as an immunosuppressive agent in certain T cell mediated autoimmune diseases.
Concentration
0.1mg/ml
Buffer
Lyophilized from 0.2μm-filtered solution in 20mM Tris, 20mM NaCl, pH8.7.
NCBI Official Name
interleukin 10
NCBI Organism
Homo sapiens
Disclaimer
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 10 ug
Lieferbar: In stock
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